Design and development of polymeric micelles with cleavable links for intracellular drug delivery
H Wei, RX Zhuo, XZ Zhang - Progress in polymer Science, 2013 - Elsevier
Driven by the urgent need in practical applications of stimuli-responsive nano-carriers for
intracellular drug delivery, the design and development of advanced polymeric micelles …
intracellular drug delivery, the design and development of advanced polymeric micelles …
pH-responsive supramolecular vesicles based on water-soluble pillar [6] arene and ferrocene derivative for drug delivery
The drug delivery system based on supramolecular vesicles that were self-assembled by a
novel host–guest inclusion complex between a water-soluble pillar [6] arene (WP6) and …
novel host–guest inclusion complex between a water-soluble pillar [6] arene (WP6) and …
Supramolecular nanostructures formed by anticancer drug assembly
We report here a supramolecular strategy to directly assemble the small molecular
hydrophobic anticancer drug camptothecin (CPT) into discrete, stable, well-defined …
hydrophobic anticancer drug camptothecin (CPT) into discrete, stable, well-defined …
Tumor redox heterogeneity‐responsive prodrug nanocapsules for cancer chemotherapy
Nanocarriers have been extensively explored for cancer drug delivery to increase the
solubility of the drug in water [1] and tumor accumulation [2] by means of its enhanced …
solubility of the drug in water [1] and tumor accumulation [2] by means of its enhanced …
Linear-dendritic drug conjugates forming long-circulating nanorods for cancer-drug delivery
Elongated micelles have many desirable characteristics for cancer-drug delivery, but they
are difficult to obtain since amphiphilic polymers form such nanostructures only within …
are difficult to obtain since amphiphilic polymers form such nanostructures only within …
Developments in the use of nanocapsules in oncology
V Yurgel, T Collares, F Seixas - Brazilian Journal of Medical and …, 2013 - SciELO Brasil
The application of nanotechnology to medicine can provide important benefits, especially in
oncology, a fact that has resulted in the emergence of a new field called Nanooncology …
oncology, a fact that has resulted in the emergence of a new field called Nanooncology …
Carrier-free functionalized multidrug nanorods for synergistic cancer therapy
We developed carrier-free multidrug nanocrystals (MDNCs) for the combination
chemotherapy with synergistic effect, improved tolerance and imaging capability for cancer …
chemotherapy with synergistic effect, improved tolerance and imaging capability for cancer …
Novel SN38 conjugate-forming nanoparticles as anticancer prodrug: in vitro and in vivo studies
The clinical utility of CPT-11 is restricted by factors such as the low conversion rate to SN38,
high interpatient variability and dose-limiting toxicity. SN38 is significantly more potent than …
high interpatient variability and dose-limiting toxicity. SN38 is significantly more potent than …
Self-assembling doxorubicin prodrug forming nanoparticles for cancer chemotherapy: synthesis and anticancer study in vitro and in vivo
P Gou, W Liu, W Mao, J Tang, Y Shen… - Journal of Materials …, 2013 - pubs.rsc.org
The clinical utility of doxorubicin (DOX) is restricted by its severe side effects. Continuous
efforts are aimed at developing efficacious DOX-delivery systems that may overcome the …
efforts are aimed at developing efficacious DOX-delivery systems that may overcome the …
One-pot construction of functional mesoporous silica nanoparticles for the tumor-acidity-activated synergistic chemotherapy of glioblastoma
Mesoporous silica nanoparticles (MSNs) have proved to be an effective carrier for controlled
drug release and can be functionalized easily for use as stimuli-responsive vehicles. Here, a …
drug release and can be functionalized easily for use as stimuli-responsive vehicles. Here, a …