Muscular dystrophy is a group of more than 30 different clinical genetic disorders that are
characterized by progressive skeletal muscle wasting and degeneration. Primary deficiency …

Duchenne muscular dystrophy (DMD) affects young boys and is characterized by the
absence of dystrophin, a large cytoskeletal protein present in skeletal and cardiac muscle …

In this article, we present a liver–kidney co‐culture model in a micro fluidic biochip. The liver
was modeled using HepG2/C3a and HepaRG cell lines and the kidney using MDCK cell …

Functional coupling between inositol (1, 4, 5)-trisphosphate receptor (IP 3 R) and ryanodine
receptor (RyR) represents a critical component of intracellular Ca 2+ signaling in many …

The cellular inhibitor of apoptosis 1 (cIAP1) protein is an essential regulator of canonical and
noncanonical nuclear factor κB (NF-κB) signaling pathways. NF-κB signaling is known to …

We have quantified Ca 2+ entry through store operated calcium channels in mice muscle
fibres, measuring the rates of change of myoplasmic [Ca 2+], d [Ca 2+] myo/dt, and of Ca 2+ …

Mutations underlying genetic cardiomyopathies might affect differentiation commitment of
resident progenitor cells. Cardiac mesoangioblasts (cM abs) are multipotent progenitor cells …

The purpose of this study was to examine the effect of hyper-osmotic stress on protein
turnover in skeletal muscle tissue using an established in-vitro model. Rat EDL muscles …

Ca 2+ sparks represent synchronous opening of the ryanodine receptor (RyR) Ca 2+
release channels located at the sarcoplasmic reticulum (SR) membrane. Whereas a quantal …