Mechanisms and clinical uses of capsaicin

SK Sharma, AS Vij, M Sharma - European journal of pharmacology, 2013 - Elsevier
Capsaicin is the active ingredient of chili peppers and gives them the characteristic pungent
flavor. Understanding the actions of capsaicin led to the discovery of its receptor, transient …

Capsinoids and related food ingredients activating brown fat thermogenesis and reducing body fat in humans

M Saito, T Yoneshiro - Current opinion in lipidology, 2013 - journals.lww.com
As human BAT may be inducible, a prolonged ingestion of capsinoids would recruit active
BAT and thereby increase energy expenditure and decrease body fat. In addition to …

Personality factors predict spicy food liking and intake

NK Byrnes, JE Hayes - Food quality and preference, 2013 - Elsevier
A number of factors likely affect the liking of capsaicin-containing foods such as social
influences, repeated exposure to capsaicin, physiological differences in chemosensation …

Spices: the savory and beneficial science of pungency

B Nilius, G Appendino - Reviews of Physiology, Biochemistry and …, 2013 - Springer
Spicy food does not only provide an important hedonic input in daily life, but has also been
anedoctically associated to beneficial effects on our health. In this context, the discovery of …

Grains of paradise (Aframomum melegueta) extract activates brown adipose tissue and increases whole-body energy expenditure in men

J Sugita, T Yoneshiro, T Hatano, S Aita… - British Journal of …, 2013 - cambridge.org
Brown adipose tissue (BAT) is responsible for cold-and diet-induced thermogenesis, and
thereby contributes to the control of whole-body energy expenditure (EE) and body fat …

Capsiate improves glucose metabolism by improving insulin sensitivity better than capsaicin in diabetic rats

DY Kwon, YS Kim, SY Ryu, MR Cha, GH Yon… - The journal of nutritional …, 2013 - Elsevier
Red peppers and red pepper paste are reported to have anti-obesity, analgesic and anti-
inflammatory effects in animals and humans due to the capsaicin in red pepper. We …

[HTML][HTML] Eight weeks of supplementation with a multi-ingredient weight loss product enhances body composition, reduces hip and waist girth, and increases energy …

HL Lopez, TN Ziegenfuss, JE Hofheins… - Journal of the …, 2013 - Springer
Background Numerous natural products are marketed and sold claiming to decrease body
weight and fat, but few undergo finished product-specific research demonstrating their safety …

Transient receptor potential activated brown fat thermogenesis as a target of food ingredients for obesity management

T Yoneshiro, M Saito - Current Opinion in Clinical Nutrition & …, 2013 - journals.lww.com
Human BAT recruited by prolonged ingestion of a vanilloid subtype one of TRP agonists
increases energy expenditure and decreases body fat. In addition to capsinoids, there are …

Transient receptor potential channels and energy homeostasis

GP Ahern - Trends in Endocrinology & Metabolism, 2013 - cell.com
Transient receptor potential (TRP) channels are members of an ancient class of ion
channels that are present in most mammalian tissues. Consistent with their wide tissue …

Manipulating molecular switches in brown adipocytes and their precursors: a therapeutic potential

A Birerdinc, M Jarrar, T Stotish, M Randhawa… - Progress in lipid …, 2013 - Elsevier
Brown adipocytes constitute a metabolically active tissue responsible for non-shivering
thermogenesis and the depletion of excess calories. Differentiation of brown fat adipocytes …