A characteristic feature of aged humans and other mammals is the debilitating, progressive
loss of skeletal muscle function and mass that is known as sarcopenia. Age-related muscle …

Carefully orchestrated intercellular communication is an essential prerequisite for the
development of multicellular organisms. In recent years, tunneling nanotubes (TNT) have …

Skeletal muscle regeneration after injury follows a remarkable sequence of synchronized
events. However, the mechanisms regulating the typical organization of the regenerating …

Myoblast fusion into multinucleated myotubes is a crucial step in skeletal muscle
development and regeneration. Here, we accumulated murine myoblasts at the ready-to …

Histological differentiation is a major pathological parameter associated with poor prognosis
in patients with pancreatic adenocarcinoma (PAC) and the molecular signature underlying …

Ferlins are large multi-C2 domain membrane proteins involved in membrane fusion and
fission events. In this study, we investigate the effects of binding of the C2 domains of …

Skeletal muscle has an impressive regenerative potential. The cells that mediate muscle
repair have unique properties that are not restricted solely to the formation of new muscle …

Дисферлинопатии—группа нервно-мышечных болезней аутосомно-рецессивного типа
наследования, при которых происходит нарушение экспрессии мРНК и (или) функции …

Dysferlinopathies is a group of autosomal-recessive inherited neuromuscular diseases,
which are characterized by defect in mRNA expression or in functionioning of dysferlin …

Cells of the ventrolateral dermomyotome delaminate and migrate into the limb buds where
they give rise to all muscles of the limbs. The migratory cells proliferate and form myoblasts …