[HTML][HTML] Human T lymphotropic virus type I (HTLV-I) oncogenesis: molecular aspects of virus and host interactions in pathogenesis of adult T cell leukemia/lymphoma …

SA Ghezeldasht, A Shirdel… - Iranian journal of …, 2013 - ncbi.nlm.nih.gov
The study of tumor viruses paves the way for understanding the mechanisms of virus
pathogenesis, including those involved in establishing infection and dissemination in the …

Therapeutic options for adult T-cell leukemia/lymphoma

A Marçais, F Suarez, D Sibon, L Frenzel… - Current oncology …, 2013 - Springer
Adult T-cell leukemia/lymphoma (ATL) is the first human malignancy associated with a
retroviral infection and occurs in approximately 5% of the 15 million to 20 million people …

[HTML][HTML] Interferon-α (IFN-α) suppresses HTLV-1 gene expression and cell cycling, while IFN-α combined with zidovudin induces p53 signaling and apoptosis in HTLV …

S Kinpara, M Kijiyama, A Takamori, A Hasegawa… - Retrovirology, 2013 - Springer
Background Human T-cell leukemia virus type-1 (HTLV-1) is the causative retrovirus of adult
T-cell leukemia/lymphoma (ATL) and HTLV-1-associated myelopathy/tropical spastic …

[HTML][HTML] Nano-encapsulation of arsenic trioxide enhances efficacy against murine lymphoma model while minimizing its impact on ovarian reserve in vitro and in vivo

RW Ahn, SL Barrett, MR Raja, JK Jozefik, L Spaho… - PloS one, 2013 - journals.plos.org
Advances in cancer therapy have increased the rate of survival of young cancer patients;
however, female lymphoma patients frequently face a temporary or permanent loss of fertility …

HTLV-1 Tax oncoprotein stimulates ROS production and apoptosis in T cells by interacting with USP10

M Takahashi, M Higuchi, GN Makokha… - Blood, The Journal …, 2013 - ashpublications.org
HTLV-1 Tax oncoprotein stimulates ROS production and apoptosis in T cells by interacting with
USP10 | Blood | American Society of Hematology Skip to Main Content Advertisement …

[HTML][HTML] The combination of arsenic, interferon-alpha, and zidovudine restores an “immunocompetent-like” cytokine expression profile in patients with adult T-cell …

G Kchour, SAR Rezaee, R Farid, A Ghantous… - Retrovirology, 2013 - Springer
Background HTLV-I associated adult T-cell leukemia/lymphoma (ATL) carries a dismal
prognosis due to chemo-resistance and immuno-compromised micro-environment. The …

[HTML][HTML] Comparison of HTLV-I proviral load in adult T cell leukemia/lymphoma (ATL), HTLV-I-associated myelopathy (HAM-TSP) and healthy carriers

MM Akbarin, H Rahimi, T HassanNia… - Iranian Journal of …, 2013 - ncbi.nlm.nih.gov
Objective (s): Human T Lymphocyte Virus Type one (HTLV-I) is a retrovirus that infects about
10-20 million people worldwide. Khorasan province in Iran is an endemic area. The majority …

Biology and treatment of HTLV-1 associated T-cell lymphomas

K Tsukasaki, K Tobinai - Best Practice & Research Clinical Haematology, 2013 - Elsevier
Adult T-cell leukemia-lymphoma (ATL) is a distinct peripheral T-lymphocytic malignancy
associated with human T-cell lymphotropic virus type I (HTLV-1) endemics in several …

[HTML][HTML] How animal models of leukaemias have already benefited patients

J Ablain, R Nasr, J Zhu, A Bazarbachi… - Molecular Oncology, 2013 - Elsevier
The relative genetic simplicity of leukaemias, the development of which likely relies on a
limited number of initiating events has made them ideal for disease modelling, particularly in …

[HTML][HTML] Combination of arsenic and interferon-α inhibits expression of KSHV latent transcripts and synergistically improves survival of mice with primary effusion …

H El Hajj, J Ali, A Ghantous, D Hodroj, A Daher… - PLoS …, 2013 - journals.plos.org
Background Kaposi sarcoma-associated herpesvirus (KSHV) is the etiologic agent of
primary effusion lymphomas (PEL). PEL cell lines infected with KSHV, but negative for …