Transient receptor potential channels in bladder function

A Avelino, A Charrua, B Frias, C Cruz… - Acta …, 2013 - Wiley Online Library
The transient receptor potential (TRP) superfamily of cationic ion channels includes proteins
involved in the transduction of several physical and chemical stimuli to finely tune …

Neuropeptide/Receptor expression and plasticity in micturition pathways

L Merrill, B Girard, L Arms, P Guertin… - Current …, 2013 - ingentaconnect.com
Several motor behaviors such as locomotion, respiration, sexual function, and micturition are
generated by rhythmic and stereotyped motor patterns of activity. In most cases, these …

Expression and function of CCL2/CCR2 in rat micturition reflexes and somatic sensitivity with urinary bladder inflammation

L Arms, BM Girard, SE Malley… - American Journal of …, 2013 - journals.physiology.org
Chemokines are proinflammatory mediators of the immune response, and there is growing
evidence for chemokine/receptor signaling involvement in pronociception. Bladder pain …

Repeated variate stress in male rats induces increased voiding frequency, somatic sensitivity, and urinary bladder nerve growth factor expression

L Merrill, S Malley, MA Vizzard - American Journal of …, 2013 - journals.physiology.org
Stress exacerbates symptoms of functional lower urinary tract disorders including interstitial
cystitis (IC)/bladder pain syndrome (BPS) and overactive bladder (OAB) in humans, but …

[HTML][HTML] Antagonism of the transient receptor potential ankyrin 1 (TRPA1) attenuates hyperalgesia and urinary bladder overactivity in cyclophosphamide-induced …

FC Meotti, S Forner, JF Lima-Garcia, AF Viana… - Chemico-biological …, 2013 - Elsevier
The aim of this study was to investigate the involvement of the transient receptor potential
ankyrin 1 (TRPA1) in haemorrhagic cystitis, the main side effect of cyclophosphamide-based …

Changes in nerve growth factor level and symptom severity following antibiotic treatment for refractory overactive bladder

G Vijaya, R Cartwright, A Derpapas, P Gallo… - International …, 2013 - Springer
Introduction and hypothesis Overactive bladder (OAB) has a multifactorial aetiology, and for
some women symptoms may be associated with chronic urothelial inflammation secondary …

Urinary nerve growth factor in children with overactive bladder: a promising, noninvasive and objective biomarker

T Oktar, T Kocak, Y Oner-Iyidogan, S Erdem… - Journal of pediatric …, 2013 - Elsevier
Objective This prospective study was designed to determine urinary nerve growth factor
(NGF) levels in children with overactive bladder (OAB), and to evaluate whether this factor …

Onabotulinumtoxin-A intradetrusorial injections modulate bladder expression of NGF, TrkA, p75 and TRPV1 in patients with detrusor overactivity

A Giannantoni, A Conte, V Farfariello, S Proietti… - Pharmacological …, 2013 - Elsevier
How onabotulinumtoxinA (onab/A) injected in the detrusor muscle improves detrusor
overactivity (DO) is still a matter of debate. Nerve growth factor (NGF) seems to play a role in …

Urinary nerve growth factor level in children with neurogenic bladder due to myelomeningocele

A Korzeniecka-Kozerska, T Porowski… - … journal of urology, 2013 - Taylor & Francis
Objective. Myelomeningocele is the most common physically disabling birth defect in
humans. It is caused by the failure of the neural tube to close and is most common in the …

Traumatic brain injury increases the risk of female urinary incontinence

JJ Keller, SP Liu, HC Lin - Neurourology and Urodynamics, 2013 - Wiley Online Library
Aims According to our knowledge, no study has attempted to explore the risk of urinary
incontinence (UI) after traumatic brain injury (TBI). This study aimed to examine the …