Cannabinoids, the active components of cannabis (Cannabis sativa) extracts, have attracted
the attention of human civilizations for centuries, much earlier than the discovery and …

Neural stem/precursor cells in the adult brain reside in the subventricular zone (SVZ) of the
lateral ventricles and the subgranular zone (SGZ) of the dentate gyrus in the hippocampus …

Cannabidiol (CBD), the main non-psychotomimetic component of the plant Cannabis sativa,
exerts therapeutically promising effects on human mental health such as inhibition of …

The endocannabinoid system has been implicated in the modulation of adult neurogenesis.
Here, we describe the effect of type 1 cannabinoid receptor (CB1R) activation on self …

After birth, stem cells in the subventricular zone (SVZ) generate neuroblasts that migrate
along the rostral migratory stream (RMS) to become interneurons in the olfactory bulb (OB) …

Signalling through EGF, FGF and endocannabinoid (eCB) receptors promotes adult
neurogenesis, and this can be modelled in culture using the Cor-1 neural stem cell line. In …

The ECs (endocannabinoids) AEA (anandamide) and 2-AG (2-arachidonoylglycerol) and
their lipid congeners OEA (N-oleoylethanolamide) and PEA (N-palmitoylethanolamide) are …

A convergent strategy was followed to modify systematically carbazole based CB 2 receptor
ligands. The length of the N-(fluoroalkyl) group (n in 7), the length of the alkanamide (m in 7) …

Neuroimmune networks and the brain endocannabinoid system contribute to the
maintenance of neurogenesis. Activation of cannabinoid receptors suppresses chronic …

Similar to clinically used antidepressants, cannabinoids can also regulate anxiety and
depressive symptoms. Although the mechanisms of these effects are not completely …