Cannabinoid receptor 2: potential role in immunomodulation and neuroinflammation

S Rom, Y Persidsky - Journal of Neuroimmune Pharmacology, 2013 - Springer
An accumulating body of evidence suggests that endocannabinoids and cannabinoid
receptors type 1 and 2 (CB 1, CB 2) play a significant role in physiologic and pathologic …

Endogenous cannabinoids revisited: a biochemistry perspective

BM Fonseca, MA Costa, M Almada… - Prostaglandins & other …, 2013 - Elsevier
Marijuana is the most commonly used illegal drug, particularly in Western societies. The
discovery of an endogenous cannabinoid system (ECS) highlighted new molecules in …

The Concise Guide to PHARMACOLOGY 2013/14: G protein‐coupled receptors

SPH Alexander, HE Benson… - British journal of …, 2013 - Wiley Online Library
Abstract The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of
the key properties of over 2000 human drug targets with their pharmacology, plus links to an …

[HTML][HTML] The endocannabinoid system, cannabinoids, and pain

PG Fine, MJ Rosenfeld - Rambam Maimonides medical journal, 2013 - ncbi.nlm.nih.gov
The endocannabinoid system is involved in a host of homeostatic and physiologic functions,
including modulation of pain and inflammation. The specific roles of currently identified …

The synthetic cannabinoid withdrawal syndrome

N Nacca, D Vatti, R Sullivan, P Sud, M Su… - Journal of addiction …, 2013 - journals.lww.com
Background: Little is known about the effects of synthetic cannabinoids. There has been only
one previous report of a withdrawal syndrome from synthetic cannabinoids. We report two …

Fat to treat fat: emerging relationship between dietary PUFA, endocannabinoids, and obesity

J Kim, Y Li, BA Watkins - Prostaglandins & other lipid mediators, 2013 - Elsevier
Obesity incidence continues to escalate as a global nutrition and health problem. Scientists
and clinicians are engaged in numerous research approaches that include behavior …

Cannabinoid Receptor CB2 Modulates Axon Guidance

G Duff, A Argaw, B Cecyre, H Cherif, N Tea, N Zabouri… - PLoS …, 2013 - journals.plos.org
Navigation of retinal projections towards their targets is regulated by guidance molecules
and growth cone transduction mechanisms. Here, we present in vitro and in vivo evidences …

Whole-Body Biodistribution and Radiation Dosimetry of the Cannabinoid Type 2 Receptor Ligand [11C]-NE40 in Healthy Subjects

R Ahmad, M Koole, N Evens, K Serdons… - Molecular imaging and …, 2013 - Springer
Purpose The type 2 cannabinoid receptor (CB2R) is part of the human endocannabinoid
system and is involved in central and peripheral inflammatory processes. In vivo imaging of …

Opioid withdrawal syndrome: emerging concepts and novel therapeutic targets

AK Rehni, AS Jaggi, N Singh - CNS & Neurological Disorders …, 2013 - ingentaconnect.com
Opioid withdrawal syndrome is a debilitating manifestation of opioid dependence and
responds poorly to the available clinical therapies. Studies from various in vivo and in vitro …

Antinociceptive effects of the selective CB2 agonist MT178 in inflammatory and chronic rodent pain models

F Vincenzi, M Targa, C Corciulo, MA Tabrizi, S Merighi… - Pain, 2013 - journals.lww.com
Antinociceptive effects of the selective CB2 agonist MT178 i... : PAIN Antinociceptive effects of
the selective CB2 agonist MT178 in inflammatory and chronic rodent pain models : PAIN …