Regenerative medicine approach to repair the failing heart

V Lionetti, C Ventura - Vascular pharmacology, 2013 - Elsevier
Heart failure is a serious and very common clinical condition in which the heart is about to
stop working. Currently, heart failure has no cure. Over the last decade, cardiac cell therapy …

Simvastatin treatment inhibits hypoxia inducible factor 1-alpha-(HIF-1alpha)-prolyl-4-hydroxylase 3 (PHD-3) and increases angiogenesis after myocardial infarction in …

M Thirunavukkarasu, V Selvaraju, NR Dunna… - International journal of …, 2013 - Elsevier
Abstract Background Statins (HMG-CoA reductase inhibitors), are known to improve cardiac
function in diabetes-induced cardiovascular disease. We investigated the mechanism by …

5. Self-Renewing Heart in the Era of Stem Cells: Who Have Saved the Heart of Prometheus?

V Lionetti - Adaptation Biology and Medicine: Volume 7, 2013 - books.google.com
The notion that the same cardiomyocytes beat throughout the lifespan of the adult human
heart, without the need for a minimum turnover, gives way to a fascinating investigation. The …

New Chemicals Drive Mesenchymal Stem Cells Towards Cardiac Cells

L Vincenzo, C Ventura - Recent Patents on Regenerative …, 2013 - ingentaconnect.com
Healthy and active stem cells are able to differentiate into mature cells of the cardiac tissue,
such as cardiomyocytes, fibroblasts and endothelial cells. Adult stem cells seem to be less …