Ceramide, the precursor of all complex sphingolipids, is a potent signaling molecule that
mediates key events of cellular pathophysiology. In the nervous system, the sphingolipid …

The enzyme acid sphingomyelinase catalyzes the hydrolysis of sphingomyelin to ceramide.
The importance of the enzyme for cell functions was first recognized in Niemann–Pick …

Sphingolipids, in particular ceramide, have been described as important components of
cellular signalling pathways. Ceramide can be produced via multiple mechanisms including …

Background: Increased expression of ceramide has been detected in emphysema.
Ceramide promotes autophagy and apoptosis, which concur with cellular homeostasis …

Ceramide is released from sphingomyelin primarily by the activity of acid, neutral, or alkaline
sphingomyelinases or is synthesized de novo. Several bacteria, viruses, and even parasites …

Purpose: Sphingolipid (SL) research reached a peak in the past years. Yet this positive trend
was not evident for eye research as the relative number of studies centered on SLs is …

[Objective] The objective of this experiment is to observe if apoptosis of the primary bovine
mammary epithelial cells could be induced by Staphylococcus aureus in vitro.[Method] …

Cystic fibrosis (CF), the most common autosomal recessive disorder, at least in western
countries, is caused by mutations of CFTR. The disease affects the intestine, the pancreas …

Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), expressed on
human epithelia, are engaged by several Gram-negative human-restricted pathogens …

Obwohl die Entdeckung von Antibiotika vielen bakteriellen Infektionen ihren Schrecken
genommen hat, können auch heute noch viele bakterielle Infektionen nicht …