Mechanistic insights into vascular calcification in CKD

R Shroff, DA Long, C Shanahan - Journal of the American Society …, 2013 - journals.lww.com
Cardiovascular disease begins early in the course of renal decline and is a life-limiting
problem in patients with CKD. The increased burden of cardiovascular disease is due, at …

Mechanisms of vascular calcification in CKD—evidence for premature ageing?

CM Shanahan - Nature Reviews Nephrology, 2013 - nature.com
Ageing is a potent, independent risk factor for cardiovascular disease. Calcification of the
vascular smooth muscle cell (VSMC) layer of the vessel media is a hallmark of vascular …

[HTML][HTML] Measurement of the prompt J/ψ and ψ (2S) polarizations in pp collisions at s= 7 TeV

S Chatrchyan, V Khachatryan, AM Sirunyan… - Physics Letters B, 2013 - Elsevier
The polarizations of prompt J/ψ and ψ (2 S) mesons are measured in proton–proton
collisions at s= 7 TeV, using a dimuon data sample collected by the CMS experiment at the …

[HTML][HTML] Fetuin-A-containing calciprotein particles reduce mineral stress in the macrophage

ER Smith, E Hanssen, LP McMahon, SG Holt - PloS one, 2013 - journals.plos.org
The formation of fetuin-A-containing calciprotein particles (CPP) may facilitate the clearance
of calcium phosphate nanocrystals from the extracellular fluid. These crystals may otherwise …

The role of fetuin-A in physiological and pathological mineralization

L Brylka, W Jahnen-Dechent - Calcified tissue international, 2013 - Springer
Mineralization in higher vertebrates is restricted to bones and teeth. Pathological
calcification is mostly known in vasculature but can basically affect all soft tissues. Simply …

Aortic valve calcification in chronic kidney disease

M Rattazzi, E Bertacco, A Del Vecchio… - Nephrology Dialysis …, 2013 - academic.oup.com
Several clinical studies reported an increased prevalence and accelerated progression of
aortic valve calcification among patients with end-stage renal disease when compared with …

Vascular calcification in end‐stage renal disease

KL Jablonski, M Chonchol - Hemodialysis International, 2013 - Wiley Online Library
Vascular calcification is highly prevalent in end‐stage renal disease and independently
predictive of future cardiovascular events and mortality. C alcification can occur in both the …

Serum fetuin‐A concentration and fetuin‐A‐containing calciprotein particles in patients with chronic inflammatory disease and renal failure

ER Smith, MM Cai, LP McMahon, E Pedagogos… - …, 2013 - Wiley Online Library
Abstract Aim Fetuin‐A (F et‐A) is an important regulator of extracellular matrix
mineralization. F et‐A plays a critical role in the formation and stabilization of high molecular …

Fetuin-A, type 2 diabetes, and risk of cardiovascular disease in older adults: the cardiovascular health study

MK Jensen, TM Bartz, KJ Mukamal, L Djoussé… - Diabetes …, 2013 - Am Diabetes Assoc
OBJECTIVE Fetuin-A, a hepatic secretory protein that simultaneously inhibits arterial
calcification and insulin action, is associated with type 2 diabetes, but its association with …

Hepcidin-25 is related to cardiovascular events in chronic haemodialysis patients

NC van der Weerd, MPC Grooteman… - Nephrology Dialysis …, 2013 - academic.oup.com
Background The development of atherosclerosis may be enhanced by iron accumulation in
macrophages. Hepcidin-25 is a key regulator of iron homeostasis, which downregulates the …