[HTML][HTML] Amyloid imaging in cognitively normal individuals, at-risk populations and preclinical Alzheimer's disease
Recent developments of PET amyloid ligands have made it possible to visualize the
presence of Aβ deposition in the brain of living participants and to assess the consequences …
presence of Aβ deposition in the brain of living participants and to assess the consequences …
Brain amyloid imaging
CC Rowe, VL Villemagne - Journal of nuclear medicine …, 2013 - Soc Nuclear Med
Imaging of brain β-amyloid plaques with 18F-labeled tracers for PET will likely be available
in clinical practice to assist the diagnosis of Alzheimer disease (AD). With the rapidly …
in clinical practice to assist the diagnosis of Alzheimer disease (AD). With the rapidly …
Early clinical PET imaging results with the novel PHF-tau radioligand [F-18]-T807
DT Chien, S Bahri, AK Szardenings… - Journal of …, 2013 - content.iospress.com
Aggregates of hyperphosphorylated tau (PHF-tau), such as neurofibrillary tangles, are linked
to the degree of cognitive impairment in Alzheimer's disease. We have developed a novel …
to the degree of cognitive impairment in Alzheimer's disease. We have developed a novel …
Amyloid-β imaging with Pittsburgh compound B and florbetapir: comparing radiotracers and quantification methods
SM Landau, C Breault, AD Joshi… - Journal of Nuclear …, 2013 - Soc Nuclear Med
11C-Pittsburgh compound B (11C-PiB) and 18F-florbetapir amyloid-β (Aβ) PET radioligands
have had a substantial impact on Alzheimer disease research. Although there is evidence …
have had a substantial impact on Alzheimer disease research. Although there is evidence …
Florbetapir (F18-AV-45) PET to assess amyloid burden in Alzheimer's disease dementia, mild cognitive impairment, and normal aging
KA Johnson, RA Sperling, CM Gidicsin… - Alzheimer's & …, 2013 - Elsevier
Objective To evaluate the performance characteristics of florbetapir F18 positron emission
tomography (PET) in patients with Alzheimer's disease (AD), mild cognitive impairment …
tomography (PET) in patients with Alzheimer's disease (AD), mild cognitive impairment …
Head-to-head comparison of 11C-PiB and 18F-AZD4694 (NAV4694) for β-amyloid imaging in aging and dementia
CC Rowe, S Pejoska, RS Mulligan… - Journal of Nuclear …, 2013 - Soc Nuclear Med
11C-Pittsburgh compound-B (11C-PiB) is the benchmark radiotracer for imaging of β-
amyloid (Aβ) plaque in Alzheimer disease (AD). 18F-labeled Aβ tracers subsequently …
amyloid (Aβ) plaque in Alzheimer disease (AD). 18F-labeled Aβ tracers subsequently …
Longitudinal amyloid imaging using 11C-PiB: methodologic considerations
BNM van Berckel, R Ossenkoppele… - Journal of Nuclear …, 2013 - Soc Nuclear Med
Several methods are in use for analyzing 11C-Pittsburgh compound-B (11C-PiB) data. The
objective of this study was to identify the method of choice for measuring longitudinal …
objective of this study was to identify the method of choice for measuring longitudinal …
Neuroimaging and other biomarkers for Alzheimer's disease: the changing landscape of early detection
SL Risacher, AJ Saykin - Annual review of clinical psychology, 2013 - annualreviews.org
The goal of this review is to provide an overview of biomarkers for Alzheimer's disease (AD),
with emphasis on neuroimaging and cerebrospinal fluid (CSF) biomarkers. We first review …
with emphasis on neuroimaging and cerebrospinal fluid (CSF) biomarkers. We first review …
Amyloid deposition detected with florbetapir F 18 (18F-AV-45) is related to lower episodic memory performance in clinically normal older individuals
RA Sperling, KA Johnson, PM Doraiswamy… - Neurobiology of …, 2013 - Elsevier
The objective of this study was to evaluate the relationship of amyloid burden, as assessed
by florbetapir F 18 (18F-AV-45) amyloid positron emission tomography, and cognition in …
by florbetapir F 18 (18F-AV-45) amyloid positron emission tomography, and cognition in …
Amyloid tracers detect multiple binding sites in Alzheimer's disease brain tissue
R Ni, PG Gillberg, A Bergfors, A Marutle, A Nordberg - Brain, 2013 - academic.oup.com
Imaging fibrillar amyloid-β deposition in the human brain in vivo by positron emission
tomography has improved our understanding of the time course of amyloid-β pathology in …
tomography has improved our understanding of the time course of amyloid-β pathology in …