[HTML][HTML] Neolignan Licarin A presents effect against Leishmania (Leishmania) major associated with immunomodulation in vitro

PLN Néris, JPA Caldas, YKS Rodrigues… - Experimental …, 2013 - Elsevier
Leishmaniasis' treatment is based mostly on pentavalent antimonials or amphotericin B long-
term administration, expensive drugs associated with severe side effects. Considering these …

Antiprotozoal activity of essential oils derived from Piper spp. grown in Colombia

SM Leal, N Pino, EE Stashenko… - Journal of Essential …, 2013 - Taylor & Francis
Plant species of the genus Piper are widely distributed throughout the Colombian territory.
Eleven Piper spp. essential oils (EO1–EO11) were chemically characterized and tested …

[HTML][HTML] Further evidence of the trypanocidal action of eupomatenoid-5: confirmation of involvement of reactive oxygen species and mitochondria owing to a reduction …

D Lazarin-Bidóia, VC Desoti, T Ueda-Nakamura… - Free Radical Biology …, 2013 - Elsevier
Our group assays natural products that are less toxic and more effective than available
nitroheterocycles as promising therapeutic options for patients with Chagas disease. Our …

The natural compounds piperovatine and piperlonguminine induce autophagic cell death on Trypanosoma cruzi

P Veiga-Santos, VC Desoti, N Miranda… - Acta tropica, 2013 - Elsevier
The currently available treatments for Chagas disease show limited therapeutic potential
and are associated with serious side effects. Our group has been attempting to find …

The Effects of N‐Butyl‐1‐(4‐dimethylamino)phenyl‐1,2,3,4‐tetrahydro‐β‐carboline‐3‐carboxamide against Leishmania amazonensis Are Mediated by …

H Volpato, VC Desoti, J Cogo… - Evidence‐Based …, 2013 - Wiley Online Library
Leishmaniasis is a disease that affects millions of people worldwide. The drugs that are
available for the treatment of this infection exhibit high toxicity and various side effects …