Helping oxytocin deliver: considerations in the development of oxytocin-based therapeutics for brain disorders

K Macdonald, D Feifel - Frontiers in neuroscience, 2013 - frontiersin.org
Concerns regarding a drought in psychopharmacology have risen from many quarters. From
one perspective, the wellspring of bedrock medications for anxiety disorders, depression …

Neuropeptides and central control of sexual behaviour from the past to the present: a review

A Argiolas, MR Melis - Progress in neurobiology, 2013 - Elsevier
Of the numerous neuropeptides identified in the central nervous system, only a few are
involved in the control of sexual behaviour. Among these, the most studied are oxytocin …

The genomics of preterm birth: from animal models to human studies

KY Bezold, MK Karjalainen, M Hallman, K Teramo… - Genome medicine, 2013 - Springer
Preterm birth (delivery at less than 37 weeks of gestation) is the leading cause of infant
mortality worldwide. So far, the application of animal models to understand human birth …

Oxytocin receptor ligand binding in embryonic tissue and postnatal brain development of the C57BL/6J mouse

EAD Hammock, P Levitt - Frontiers in behavioral neuroscience, 2013 - frontiersin.org
Oxytocin (OXT) has drawn increasing attention as a developmentally relevant neuropeptide
given its role in the brain regulation of social behavior. It has been suggested that OXT plays …

Melatonin and the circadian timing of human parturition

J Olcese, S Lozier, C Paradise - Reproductive Sciences, 2013 - journals.sagepub.com
Although the onset of spontaneous human parturition has long been known to occur
preferentially during the nighttime and early morning hours, no convincing physiological …

Oxytocin modulates social interaction but is not essential for sexual behavior in male mice

VM Lazzari, RO Becker, MS de Azevedo… - Behavioural brain …, 2013 - Elsevier
Recently, several studies have shown different conclusions regarding the effect of oxytocin
(OT) on the social behaviors of male mice. Most of these studies used exogenous OT, but …

Sexual behavior and dendritic spine density of posterodorsal medial amygdala neurons in oxytocin knockout female mice

RO Becker, VM Lazzari, IC Menezes, M Morris… - Behavioural brain …, 2013 - Elsevier
Central oxytocin (OT) and arginine-vasopressin (AVP) have been shown to play an
important role in sexual behavior and neuroendocrine secretion in rodents. The results of …

Oxytocin, vasopressin, and the evolution of mating systems in mammals

SM Freeman, L Young - … , vasopressin and related peptides in the …, 2013 - books.google.com
8.1 Introduction u: 4 “Safety in numbers. Pack mentality."“All for one and one for all." Our
language is full of phrases like these, expressing the almost instinctual human …

[HTML][HTML] Molecular analysis of parturition via oxytocin receptor expression

T Kimura, K Ogita, K Kumasawa, T Tomimatsu… - Taiwanese Journal of …, 2013 - Elsevier
In daily obstetric practice, oxytocin is one of the most frequently used drugs to stimulate
uterine contraction. However, uterine sensitivity to oxytocin is profoundly different among …

Voluntary sodium ingestion in wild-type and oxytocin knockout mice

RR Vollmer, HM Cai, JA Miedlar… - Clinical and Experimental …, 2013 - Taylor & Francis
Oxytocin knockout (OT KO) mice acutely consume inappropriate amounts of sodium
following overnight water deprivation suggesting that oxytocinergic neurons inhibit …