The thalamus and multiple sclerosis: modern views on pathologic, imaging, and clinical aspects

A Minagar, MH Barnett, RHB Benedict, D Pelletier… - Neurology, 2013 - AAN Enterprises
The paired thalamic nuclei are gray matter (GM) structures on both sides of the third ventricle
that play major roles in cortical activation, relaying sensory information to the higher cortical …

Localized grey matter atrophy in multiple sclerosis: a meta-analysis of voxel-based morphometry studies and associations with functional disability

J Lansley, D Mataix-Cols, M Grau, J Radua… - Neuroscience & …, 2013 - Elsevier
Grey matter (GM) damage in Multiple Sclerosis (MS) occurs largely independent of white
matter (WM) lesions and shows stronger correlation with clinical parameters than WM …

Thalamic atrophy is associated with development of clinically definite multiple sclerosis

R Zivadinov, E Havrdová, N Bergsland, M Tyblova… - Radiology, 2013 - pubs.rsna.org
Purpose To investigate the association between the development of thalamic and cortical
atrophy and the conversion to clinically definite multiple sclerosis (CDMS) in patients with …

[HTML][HTML] Assessing the correlation between grey and white matter damage with motor and cognitive impairment in multiple sclerosis patients

E Sbardella, N Petsas, F Tona, L Prosperini, E Raz… - PloS one, 2013 - journals.plos.org
Background Multiple sclerosis (MS) is characterized by demyelinating and degenerative
processes within the central nervous system. Unlike conventional MRI, new advanced …

Evolution of cortical and thalamus atrophy and disability progression in early relapsing-remitting MS during 5 years

R Zivadinov, N Bergsland, O Dolezal… - American Journal …, 2013 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Pathologic changes in GM have an important role in MS.
We investigated the association between SDGM and cortical volume changes and disability …

White-matter lesions drive deep gray-matter atrophy in early multiple sclerosis: support from structural MRI

M Mühlau, D Buck, A Förschler… - Multiple Sclerosis …, 2013 - journals.sagepub.com
Background: In MS, the relationship between lesions within cerebral white matter (WM) and
atrophy within deep gray matter (GM) is unclear. Objective: To investigate the spatial …

Expanded functional coupling of subcortical nuclei with the motor resting-state network in multiple sclerosis

AM Dogonowski, HR Siebner… - Multiple Sclerosis …, 2013 - journals.sagepub.com
Background: Multiple sclerosis (MS) impairs signal transmission along cortico-cortical and
cortico-subcortical connections, affecting functional integration within the motor network …

Influence of personality on the relationship between gray matter volume and neuropsychiatric symptoms in multiple sclerosis

RHB Benedict, CE Schwartz, P Duberstein… - Psychosomatic …, 2013 - journals.lww.com
Objective Research has revealed an association between personality traits and health
outcomes, and in multiple sclerosis (MS), there are preliminary data showing a correlation …

[HTML][HTML] Brain atrophy: an in-vivomeasure of disease activity in multiple sclerosis

EW Radü, K Bendfeldt, N Mueller-Lenke, S Magon… - Swiss medical …, 2013 - smw.ch
Multiple sclerosis (MS) has traditionally been considered to be primarily an inflammatory
demyelinating disorder. Nowadays it is recognised as both an inflammatory and a …

Imaging cortical damage and dysfunction in multiple sclerosis

M Filippi, MA Rocca, MA Horsfield, S Hametner… - JAMA …, 2013 - jamanetwork.com
In line with pathological investigations, in vivo magnetic resonance imaging has consistently
shown both focal and diffuse damage in the cerebral cortex of patients with multiple …