The gut microbiota—masters of host development and physiology
F Sommer, F Bäckhed - Nature reviews microbiology, 2013 - nature.com
Establishing and maintaining beneficial interactions between the host and its associated
microbiota are key requirements for host health. Although the gut microbiota has previously …
microbiota are key requirements for host health. Although the gut microbiota has previously …
The role of cytokines in inflammatory bone loss
PPC Souza, UH Lerner - Immunological investigations, 2013 - Taylor & Francis
Chronic inflammatory processes close to bone often lead to loss of bone in diseases such as
rheumatoid arthritis, periodontitis, loosened joint prosthesis and tooth implants. This is …
rheumatoid arthritis, periodontitis, loosened joint prosthesis and tooth implants. This is …
Osteoimmunology and the influence of pro-inflammatory cytokines on osteoclasts
J Zupan, M Jeras, J Marc - Biochemia medica, 2013 - hrcak.srce.hr
Sažetak Bone and immune system are functionally interconnected. Immune and bone cells
derive from same progenitors in the bone marrow, they share a common microenvironment …
derive from same progenitors in the bone marrow, they share a common microenvironment …
Dynamic visualization of RANKL and Th17-mediated osteoclast function
J Kikuta, Y Wada, T Kowada, Z Wang… - The Journal of …, 2013 - Am Soc Clin Investig
Osteoclasts are bone resorbing, multinucleate cells that differentiate from mononuclear
macrophage/monocyte-lineage hematopoietic precursor cells. Although previous studies …
macrophage/monocyte-lineage hematopoietic precursor cells. Although previous studies …
The interplay between the bone and the immune system
In the last two decades, numerous scientists have highlighted the interactions between bone
and immune cells as well as their overlapping regulatory mechanisms. For example …
and immune cells as well as their overlapping regulatory mechanisms. For example …
Advances in osteoclast biology reveal potential new drug targets and new roles for osteoclasts
BF Boyce - Journal of Bone and Mineral Research, 2013 - academic.oup.com
Osteoclasts are multinucleated myeloid lineage cells formed in response to macrophage
colony‐stimulating factor (M‐CSF) and receptor activator of NF‐κB ligand (RANKL) by fusion …
colony‐stimulating factor (M‐CSF) and receptor activator of NF‐κB ligand (RANKL) by fusion …
Th17 cells and IL-17 a—focus on immunopathogenesis and immunotherapeutics
WB van den Berg, IB McInnes - Seminars in arthritis and rheumatism, 2013 - Elsevier
abstract Importance Accumulating evidence suggests that IL-17 A has broad pathogenic
roles in multiple autoimmune and immune-mediated inflammatory diseases, including …
roles in multiple autoimmune and immune-mediated inflammatory diseases, including …
Th17 Cells in Immunopathogenesis and treatment of rheumatoid arthritis
G Azizi, F Jadidi‐Niaragh… - International journal of …, 2013 - Wiley Online Library
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by the
sequestration of various leukocyte subpopulations within both the developing pannus and …
sequestration of various leukocyte subpopulations within both the developing pannus and …
Macrophage subsets and osteoimmunology: tuning of the immunological recognition and effector systems that maintain alveolar bone
C Sima, M Glogauer - Periodontology 2000, 2013 - Wiley Online Library
Chronic and aggressive periodontal diseases are characterized by the failure to resolve
local inflammation against periodontopathogenic bacteria in the subgingival biofilm …
local inflammation against periodontopathogenic bacteria in the subgingival biofilm …
Levels of circulating Th17 cells and regulatory T cells in ankylosing spondylitis patients with an inadequate response to anti− TNF-α therapy
L Xueyi, C Lina, W Zhenbiao, H Qing, L Qiang… - Journal of clinical …, 2013 - Springer
Purpose To investigate the effects of TNF-α blockage on levels of circulating Th17, Treg and
their related cytokines in ankylosing spondylitis (AS) patients with different response to anti …
their related cytokines in ankylosing spondylitis (AS) patients with different response to anti …