Pathology imaging informatics for quantitative analysis of whole-slide images

S Kothari, JH Phan, TH Stokes… - Journal of the American …, 2013 - academic.oup.com
Objectives With the objective of bringing clinical decision support systems to reality, this
article reviews histopathological whole-slide imaging informatics methods, associated …

Molecular pathology via IR and Raman spectral imaging

M Diem, A Mazur, K Lenau, J Schubert… - Journal of …, 2013 - Wiley Online Library
During the last 15 years, vibrational spectroscopic methods have been developed that can
be viewed as molecular pathology methods that depend on sampling the entire genome …

[HTML][HTML] Going fully digital: Perspective of a Dutch academic pathology lab

N Stathonikos, M Veta, A Huisman… - Journal of pathology …, 2013 - Elsevier
During the last years, whole slide imaging has become more affordable and widely
accepted in pathology labs. Digital slides are increasingly being used for digital archiving of …

Digital pathology consultations—a new era in digital imaging, challenges and practical applications

G Romero Lauro, W Cable, A Lesniak, E Tseytlin… - Journal of digital …, 2013 - Springer
Digital pathology has grown dramatically in the last 10 years and has created opportunities
to not only support the triaging of difficult cases among specialists within an organization, but …

[HTML][HTML] Eliminating tissue-fold artifacts in histopathological whole-slide images for improved image-based prediction of cancer grade

S Kothari, JH Phan, MD Wang - Journal of pathology informatics, 2013 - Elsevier
Background: Analysis of tissue biopsy whole-slide images (WSIs) depends on effective
detection and elimination of image artifacts. We present a novel method to detect tissue-fold …

Digital slide imaging in cervicovaginal cytology: a pilot study

AM Wright, D Smith, B Dhurandhar… - … of pathology and …, 2013 - meridian.allenpress.com
Context.—Digital whole slide imaging is the anticipated future of anatomic pathology, where
sign-out of glass slides will be replaced by scanned images. Whole slide imaging has been …

Evaluation of mitotic activity index in breast cancer using whole slide digital images

S Al-Janabi, HJ van Slooten, M Visser… - PloS one, 2013 - journals.plos.org
Introduction Mitotic Activity Index (MAI) is an important independent prognostic factor and an
integral part of the breast cancer grading system. Thus, correct estimation of this …

EM-based segmentation-driven color standardization of digitized histopathology

A Basavanhally, A Madabhushi - Medical Imaging 2013 …, 2013 - spiedigitallibrary.org
The development of tools for the processing of color images is often complicated by
nonstandardness–the notion that different image regions corresponding to the same tissue …

Validation of a new classifier for the automated analysis of the human epidermal growth factor receptor 2 (HER2) gene amplification in breast cancer specimens

D Furrer, S Jacob, C Caron, F Sanschagrin… - Diagnostic …, 2013 - Springer
Amplification of the human epidermal growth factor receptor 2 (HER2) is a prognostic marker
for poor clinical outcome and a predictive marker for therapeutic response to targeted …

Reliability of whole slide images as a diagnostic modality for renal allograft biopsies

KY Jen, JL Olson, S Brodsky, XJ Zhou, T Nadasdy… - Human pathology, 2013 - Elsevier
The use of digital whole slide images (WSI) in the field of pathology has become feasible for
routine diagnostic purposes and has become more prevalent in recent years. This type of …