The noninfectious HIV-1 transgenic (HIV-1Tg) rat was developed as a model of AIDs-related
pathology and immune dysfunction by manipulation of a noninfectious HIV-1gag-pol virus …

N-linked glycans attached to specific amino acids of the gp120 envelope trimer of a HIV
virion can modulate the binding affinity of gp120 to CD4, influence coreceptor tropism, and …

Context: People infected with HIV have a higher risk for developing insulin resistance,
diabetes, and cardiovascular disease than the general population. Dipeptidyl peptidase IV …

Chemokines constitute a large family of small proteins that regulate leukocyte trafficking to
the site of inflammation by binding to specific cell‐surface receptors belonging to the G …

The human immunodeficiency virus type 1 (HIV‐1) uses CD4 and the co‐receptor CCR5 or
CXCR4 in the process of cell entry. The negatively charged extracellular domains of CXCR4 …

Strong adaptive evolutionary forces shape the interactions between pathogens and their
hosts and typically lead to a stable co-existence. In this process of co-evolution, mammals …

HIV/AIDS occurrence is a major health problem facing all countries in the world. Cutaneous
manifestations are common findings in HIV infected patients. Certain characteristic skin …

The nucleolus is a plurifunctional organelle with dynamic protein exchange involved in
diverse aspects of cell biology. Additionally, the nucleolus has been shown to have a role in …

BANGAN JOHN The single nucleotide polymorphisms (SNPs) in CCR5 (-2459 G> A
[promoter], Δ32 deletion polymorphism [open reading frame, ORF]) influences the …

Résumé L'infection par le virus de l'immunodéficience humaine de type 1 (VIH-1) entraîne le
dysfonctionnement du système immunitaire menant à la déplétion de lymphocytes TCD4 …