[HTML][HTML] Abnormal Ca2+ homeostasis, atrial arrhythmogenesis, and sinus node dysfunction in murine hearts modeling RyR2 modification

Y Zhang, GDK Matthews, M Lei, CLH Huang - Frontiers in Physiology, 2013 - frontiersin.org
Ryanodine receptor type 2 (RyR2) mutations are implicated in catecholaminergic
polymorphic ventricular tachycardia (CPVT) thought to result from altered myocyte Ca2+ …

Loss of Nav1.5 expression and function in murine atria containing the RyR2-P2328S gain-of-function mutation

JH King, C Wickramarachchi, K Kua, Y Du… - Cardiovascular …, 2013 - academic.oup.com
Aims Recent studies reported slowed conduction velocity (CV) in murine hearts
homozygous for the gain-of-function RyR2-P2328S mutation (RyR2S/S) and associated this …

[HTML][HTML] Atrial arrhythmogenesis in catecholaminergic polymorphic ventricular tachycardia–is there a mechanistic link between sarcoplasmic reticulum Ca2+ leak and …

J Heijman, XHT Wehrens, D Dobrev - Acta physiologica (Oxford …, 2013 - ncbi.nlm.nih.gov
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is caused by mutations in
the genes encoding the cardiac ryanodine receptor channel (RyR2) or the major …

Bridging the dimensions of research on cardiac ryanodine receptor mutations.

C Napolitano - Journal of Cardiovascular Electrophysiology, 2013 - search.ebscohost.com
The author discusses research results on the role for slow electrical conduction in the
ryanodine receptor RyR2-dependent catecholaminergic polymorphic ventricular tachycardia …

[PDF][PDF] LossofNav1. 5expressionandfunctioninmurineatria containing the RyR2-P2328S gain-of-function mutation

JH King, C Wickramarachchi, K Kua, Y Du… - scholar.archive.org
Aims Recent studies reported slowed conduction velocity (CV) in murine hearts
homozygous for the gain-of-function RyR2-P2328S mutation (RyR2S/S) and associated this …