Metabolomics and ischaemic heart disease

AA Rasmiena, TW Ng, PJ Meikle - Clinical science, 2013 - portlandpress.com
Ischaemic heart disease accounts for nearly half of the global cardiovascular disease
burden. Aetiologies relating to heart disease are complex, but dyslipidaemia, oxidative …

Identification of two genes potentially associated in iron-heme homeostasis in human carotid plaque using microarray analysis

H Ayari, G Bricca - Journal of biosciences, 2013 - Springer
Classic characteristics are poor predictors of the risk of thromboembolism. Thus, better
markers for the carotid atheroma plaque formation and symptom causing are needed. Our …

MRI of carotid atherosclerosis

WS Kerwin, T Hatsukami, C Yuan… - American journal of …, 2013 - Am Roentgen Ray Soc
OBJECTIVE. Although MRI is widely used to observe atherosclerosis impacts on the vessel
lumen, MRI also depicts the size of the plaque itself, its composition, and plaque …

Understanding symptomatology of atherosclerotic plaque by image-based tissue characterization

UR Acharya, O Faust, APC Alvin… - Computer methods and …, 2013 - Elsevier
Characterization of carotid atherosclerosis and classification into either symptomatic or
asymptomatic is crucial in terms of diagnosis and treatment planning for a range of …

[HTML][HTML] Sex-related differences in carotid plaque features and inflammation

G Sangiorgi, S Roversi, GB Zoccai, MG Modena… - Journal of vascular …, 2013 - Elsevier
OBJECTIVE: Severe carotid stenosis is a frequent cause of stroke in both men and women.
Whereas several sex-related comparisons are available on coronary atherosclerosis, there …

Pregnancy-specific glycoproteins bind integrin αIIbβ3 and inhibit the platelet—fibrinogen interaction

DK Shanley, PA Kiely, K Golla, S Allen, K Martin… - PloS one, 2013 - journals.plos.org
Pregnancy-specific glycoproteins (PSGs) are immunoglobulin superfamily members
encoded by multigene families in rodents and primates. In human pregnancy, PSGs are …

Multimodality imaging of carotid atherosclerotic plaque: Going beyond stenosis

D Hingwala, C Kesavadas, PN Sylaja… - Indian Journal of …, 2013 - thieme-connect.com
Apart from the degree of stenosis, the morphology of carotid atherosclerotic plaques and
presence of neovascularization are important factors that may help to evaluate the risk …

[HTML][HTML] Increased platelet activation in early symptomatic vs. asymptomatic carotid stenosis and relationship with microembolic status: results from the Platelets and …

JA Kinsella, WO Tobin, S Tierney, TM Feeley… - Journal of Thrombosis …, 2013 - Elsevier
Background Cerebral microembolic signals (MES) may predict increased stroke risk in
carotid stenosis. However, the relationship between platelet counts or platelet activation …

Novel 3D ultrasound image-based biomarkers based on a feature selection from a 2D standardized vessel wall thickness map: a tool for sensitive assessment of …

B Chiu, B Li, TWS Chow - Physics in Medicine & Biology, 2013 - iopscience.iop.org
With the advent of new therapies and management strategies for carotid atherosclerosis,
there is a parallel need for measurement tools or biomarkers to evaluate the efficacy of these …

Platelet activation, function, and reactivity in atherosclerotic carotid artery stenosis: a systematic review of the literature

JA Kinsella, WO Tobin, G Hamilton… - … Journal of Stroke, 2013 - journals.sagepub.com
An important proportion of transient ischemic attack or ischemic stroke is attributable to
moderate or severe (50–99%) atherosclerotic carotid stenosis or occlusion. Platelet …