A molecular motor is made of either a single macromolecule or a macromolecular complex.
Just like their macroscopic counterparts, molecular motors “transduce” input energy into …

Innovation and new molecular entity production by the pharmaceutical industry has been
below expectations. Surprisingly, more first-in-class small-molecule drugs approved by the …

We present an experimental and computational pipeline for the generation of kinetic models
of metabolism, and demonstrate its application to glycolysis in Saccharomyces cerevisiae …

Despite the sequencing of the human genome, the rate of innovative and successful drug
discovery in the pharmaceutical industry has continued to decrease. Leaving aside …

The rate of traumatic brain injury (TBI) in service members with wartime injuries has risen
rapidly in recent years, and complex, variable links have emerged between TBI and long …

The mountains of data thrusting from the new landscape of modern high-throughput biology
are irrevocably changing biomedical research and creating a near-insatiable demand for …

Our planet's soils teem with microorganisms that regulate processes from crop productivity to
carbon sequestration. Molecular analysis contributes hugely to the characterization of …

Final draft for CAFF board review of the Arctic Terrestrial Biodiversity Monitoring Plan/CAFF
Monitoring Series Report No. 7. Presented at the Arctic Council's Senior Arctic Officials …

Objective We describe an approach for modeling temporal relationships in a large scale
association analysis of electronic health record data. The addition of temporal information …

We live in exciting times with the prospects of postgenomics diagnostics. Metabolomics is a
novel “omics” data-intensive science that is accelerating the development of postgenomics …