Arylamine N‐acetyltransferases: a structural perspective

X Zhou, Z Ma, D Dong, B Wu - British journal of pharmacology, 2013 - Wiley Online Library
Arylamine N‐acetyltransferase (NAT) plays an important role in metabolism and
detoxification of many compounds including drugs and environmental carcinogens through …

Structure of arylamine N-acetyltransferase from Mycobacterium tuberculosis determined by cross-seeding with the homologous protein from M. marinum: triumph over …

A Abuhammad, ED Lowe, MA McDonough… - … Section D: Biological …, 2013 - scripts.iucr.org
Arylamine N-acetyltransferase from Mycobacterium tuberculosis (TBNAT) plays an important
role in the intracellular survival of the microorganism inside macrophages. Medicinal …

Synthesis and bioevaluation of some new isoniazid derivatives

L Matei, C Bleotu, I Baciu, C Draghici, P Ionita… - Bioorganic & medicinal …, 2013 - Elsevier
The aim of the study was to synthesize some new compounds with potential anti-
tuberculosis activity, containing isoniazid and α, β-unsaturated thiocinnamamide-like …

Identification of the Enzyme Responsible for N-Acetylation of Norfloxacin by Microbacterium sp. Strain 4N2-2

DW Kim, J Feng, H Chen, O Kweon, Y Gao… - Applied and …, 2013 - Am Soc Microbiol
ABSTRACT Microbacterium sp. 4N2-2, isolated from a wastewater treatment plant, converts
the antibacterial fluoroquinolone norfloxacin to N-acetylnorfloxacin and three other …

[PDF][PDF] The biological role of prokaryotic and eukaryotic N-acetyltransferase

A Zabost, Z Zwolska… - Advances in …, 2013 - journals.viamedica.pl
Abstract The N-acetyltransferases (NAT; EC 2.3. 1.5) are involved in the metabolism of drugs
and environmental toxins. They catalyse the acetyl transfer from acetyl coenzyme A to an …

Rola biologiczna prokariotycznych i eukariotycznych N-acetylotransferaz

A Zabost, Z Zwolska… - Advances in Respiratory …, 2013 - mdpi.com
Abstract N-acetylotransferazy (NAT; EC2. 3.1. 5) biorą czynny udział w metabolizowaniu
leków i toksyn środowiskowych. Katalizują przeniesienie grupy acetylowej z …

[PDF][PDF] Structure of arylamine N-acetyltransferase from

A Abuhammad, ED Lowe, A Michael - 2013 - academia.edu
Mycobacterium tuberculosis is still the leading cause of death worldwide by an infectious
agent. Despite the recent reduction in cases of tuberculosis (TB), the global burden remains …