Ethanol induces TLR 4/TLR 2 association, triggering an inflammatory response in microglial cells

S Fernandez‐Lizarbe, J Montesinos… - Journal of …, 2013 - Wiley Online Library
Alcohol consumption can induce brain damage, demyelination, and neuronal death,
although the mechanisms are poorly understood. Toll‐like receptors are sensors of the …

Therapeutic role of toll-like receptor modification in cardiovascular dysfunction

A Navi, H Patel, S Shaw, D Baker, J Tsui - Vascular pharmacology, 2013 - Elsevier
Toll-like receptors (TLR) are key pattern recognition receptors in the innate immune system.
The TLR-mediated immune response against pathogens is usually protective however …

[图书][B] Cardiovascular diseases: Nutritional and therapeutic interventions

N Maulik - 2013 - books.google.com
With cardiovascular disease remaining one of the primary causes of morbidity and mortality
worldwide, there is a great need to further understand the molecular basis of this disease …