Highlights•SIMS is the predominant imaging mass spectrometry (IMS) technique for single-
cell MS imaging.•SIMS at subcellular spatial resolution has led to new biological …

Imaging mass spectrometry (IMS) has been a useful tool for investigating protein, peptide,
drug and metabolite distributions in human and animal tissue samples for almost 15 years …

The acquisition of localized molecular spectra with mass spectrometry imaging (MSI) has a
great, but as yet not fully realized, potential for biomedical diagnostics and research. The …

This article gives an overview of some of the most recent trends in mass-spectrometry (MS)-
based approaches and their application in food metabolomics. MS is a powerful analytical …

Despite the tendency to regard tumors as a simple mass of cancer cells, tumors have a high
degree of complexity that is difficult to access with most analytical methods. Because the …

Mass spectrometry imaging (MSI) methods and protocols have become widely adapted to a
variety of tissues and species. However, the MSI literature contains minimal information on …

As the only imaging method available, Imaging Mass Spectrometry (IMS) can determine
both the identity and the distribution of hundreds of molecules on tissue sections, all in one …

Mass spectrometry (MS) was used to measure the concentrations of drug and biological
compounds in plasma and tissues. Matrix‐assisted laser desorption/ionization (MALDI) …

Imaging mass spectrometry (IMS) is an emergent and innovative approach for measuring
the composition, abundance and regioselectivity of molecules within an investigated area of …

Matrix-assisted laser desorption/ionization mass spectrometry imaging is an emerging
powerful technique in drug metabolism and pharmacokinetics research. Despite recent …