The transcription factor FOXM1 (Forkhead box M1): proliferation-specific expression, transcription factor function, target genes, mouse models, and normal biological …
I Wierstra - Advances in cancer research, 2013 - Elsevier
Abstract FOXM1 (Forkhead box M1) is a typical proliferation-associated transcription factor,
which stimulates cell proliferation and exhibits a proliferation-specific expression pattern …
which stimulates cell proliferation and exhibits a proliferation-specific expression pattern …
FOXM1 (Forkhead box M1) in tumorigenesis: overexpression in human cancer, implication in tumorigenesis, oncogenic functions, tumor-suppressive properties, and …
I Wierstra - Advances in cancer research, 2013 - Elsevier
Abstract FOXM1 (Forkhead box M1) is a typical proliferation-associated transcription factor
and is also intimately involved in tumorigenesis. FOXM1 stimulates cell proliferation and cell …
and is also intimately involved in tumorigenesis. FOXM1 stimulates cell proliferation and cell …
Identification of cell cycle–regulated genes periodically expressed in U2OS cells and their regulation by FOXM1 and E2F transcription factors
GD Grant, L Brooks 3rd, X Zhang… - Molecular biology of …, 2013 - Am Soc Cell Biol
We identify the cell cycle–regulated mRNA transcripts genome-wide in the osteosarcoma-
derived U2OS cell line. This results in 2140 transcripts mapping to 1871 unique cell cycle …
derived U2OS cell line. This results in 2140 transcripts mapping to 1871 unique cell cycle …
[HTML][HTML] Computational purification of individual tumor gene expression profiles leads to significant improvements in prognostic prediction
Tumor heterogeneity is a limiting factor in cancer treatment and in the discovery of
biomarkers to personalize it. We describe a computational purification tool, ISOpure, which …
biomarkers to personalize it. We describe a computational purification tool, ISOpure, which …
Neil3, the final frontier for the DNA glycosylases that recognize oxidative damage
DNA glycosylases are the enzymes that initiate the Base Excision Repair (BER) process that
protects all organisms from the mutagenic and/or cytotoxic effects of DNA base lesions …
protects all organisms from the mutagenic and/or cytotoxic effects of DNA base lesions …
Analysis of variable retroduplications in human populations suggests coupling of retrotransposition to cell division
A Abyzov, R Iskow, O Gokcumen, DW Radke… - Genome …, 2013 - genome.cshlp.org
In primates and other animals, reverse transcription of mRNA followed by genomic
integration creates retroduplications. Expressed retroduplications are either “retrogenes” …
integration creates retroduplications. Expressed retroduplications are either “retrogenes” …
Transcription profiling during the cell cycle shows that a subset of Polycomb-targeted genes is upregulated during DNA replication
J Pena-Diaz, SA Hegre, E Anderssen… - Nucleic acids …, 2013 - academic.oup.com
Genome-wide gene expression analyses of the human somatic cell cycle have indicated
that the set of cycling genes differ between primary and cancer cells. By identifying genes …
that the set of cycling genes differ between primary and cancer cells. By identifying genes …
[HTML][HTML] The cytoskeletal protein RHAMM and ERK1/2 activity maintain the pluripotency of murine embryonic stem cells
J Jiang, P Mohan, CA Maxwell - PLoS One, 2013 - journals.plos.org
Receptor for hyaluronan mediated motility (RHAMM, encoded by HMMR) may be a cell-
surface receptor for hyaluronan that regulates embryonic stem cell pluripotency and …
surface receptor for hyaluronan that regulates embryonic stem cell pluripotency and …
Assessment of the usefulness of the murine cytotoxic T cell line CTLL-2 for immunotoxicity screening by transcriptomics
PCJ Schmeits, OL Volger, ET Zandvliet, H van Loveren… - Toxicology Letters, 2013 - Elsevier
A toxicogenomics approach was applied to assess the usefulness of the mouse cytotoxic T
cell line CTLL-2 for in vitro immunotoxicity testing. CTLL-2 cells were exposed for 6h to two …
cell line CTLL-2 for in vitro immunotoxicity testing. CTLL-2 cells were exposed for 6h to two …
[HTML][HTML] Transcription factor binding profiles reveal cyclic expression of human protein-coding genes and non-coding RNAs
Cell cycle is a complex and highly supervised process that must proceed with regulatory
precision to achieve successful cellular division. Despite the wide application, microarray …
precision to achieve successful cellular division. Despite the wide application, microarray …