Regulation of the MIR155 host gene in physiological and pathological processes

TS Elton, H Selemon, SM Elton, NL Parinandi - Gene, 2013 - Elsevier
MicroRNAs (miRNAs), a family of small nonprotein-coding RNAs, play a critical role in
posttranscriptional gene regulation by acting as adaptors for the miRNA-induced silencing …

miR‐223: infection, inflammation and cancer

M Haneklaus, M Gerlic, LAJ O'Neill… - Journal of internal …, 2013 - Wiley Online Library
Expression of the micro RNA miR‐223 is deregulated during influenza or hepatitis B
infection and in inflammatory bowel disease, type 2 diabetes, leukaemia and lymphoma …

Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia

Cancer Genome Atlas Research … - New England Journal of …, 2013 - Mass Medical Soc
Background Many mutations that contribute to the pathogenesis of acute myeloid leukemia
(AML) are undefined. The relationships between patterns of mutations and epigenetic …

The impact of hemolysis on cell-free microRNA biomarkers

MB Kirschner, JJB Edelman, SCH Kao… - Frontiers in …, 2013 - frontiersin.org
Cell-free microRNAs in plasma and serum have become a promising source of biomarkers
for various diseases. Despite rapid progress in this field, there remains a lack of consensus …

Micro RNA s in platelet production and activation

LC Edelstein, SE McKenzie, C Shaw… - … of Thrombosis and …, 2013 - Wiley Online Library
Recent work by the E ncyclopedia of DNA Elements project showed that non‐protein‐coding
RNA s account for an unexpectedly large proportion of the human genome. Among these …

Genistein down-regulates miR-223 expression in pancreatic cancer cells

J Ma, L Cheng, H Liu, J Zhang, Y Shi, F Zeng… - Current drug …, 2013 - ingentaconnect.com
Although genistein has been shown to inhibit tumorigenesis in a variety of human cancers
including pancreatic cancer (PC), the exact molecular mechanism of its anti-cancer effects …

miR-142-3p regulates the formation and differentiation of hematopoietic stem cells in vertebrates

X Lu, X Li, Q He, J Gao, Y Gao, B Liu, F Liu - Cell research, 2013 - nature.com
Previous studies on developmental hematopoiesis have mainly focused on signaling and
transcription factors, while the appreciation of epigenetic regulation including that of …

Critical differences in hematopoiesis and lymphoid development between humans and mice

C Parekh, GM Crooks - Journal of clinical immunology, 2013 - Springer
During the last five decades, elegant mouse models of hematopoiesis have yielded most of
the seminal insights into this complex biological system of self-renewal and lineage …

MicroRNAs in hematological malignancies

CH Lawrie - Blood reviews, 2013 - Elsevier
MicroRNAs (miRNAs) have become one of the hottest topics in biology over recent years,
but remarkably have only been formally recognized for just over 10years. These …

Streptavidin-enhanced surface plasmon resonance biosensor for highly sensitive and specific detection of microRNA

D Zhang, Y Yan, W Cheng, W Zhang, Y Li, H Ju… - Microchimica Acta, 2013 - Springer
We are presenting a method for sensitive and specific detection of microRNA (miRNA) using
surface plasmon resonance. A thiolated capture DNA probe with a short complete …