Significance: Oxygen and circadian rhythmicity are essential in a myriad of physiological
processes to maintain homeostasis, from blood pressure and sleep/wake cycles, down to …

Mammals are born with an immature circadian system, which completes its development
postnatally. Evidence suggests that the environment experienced by a newborn will impact …

Glucocorticoid (GC) signaling synchronizes the circadian rhythm of individual peripheral
cells and induces the expression of circadian genes, including Period1 (Per1) and Period2 …

Few challenges are more critical to the survival of a species than reproduction. To ensure
reproductive success, myriad aspects of physiology and behaviour need to be tightly …

Background As economically relevant traits, feeding behavior and food preference
domestication determine production cost and profitability. Although there are intensive …

Disruption of pancreatic clock genes impairs pancreatic beta-cell function, leading to the
onset of diabetes. Despite the importance of pancreatic alpha-cells in the regulation of …

В обзоре рассмотрены современные представления о молекулярно-генетических
механизмах, лежащих в основе циркадианной системы. Обобщены данные о …

The suprachiasmatic nucleus (SCN) provides timing to the brain and to the whole organism.
Its rhythmic signal to mainly hypothalamic structures results in a synchronized hormonal and …

Runx2, a member of the family of runt-related transcription factors, is rhythmically expressed
in bone and may be involved in circadian rhythms in bone homeostasis and osteogenesis …

Light-stimulated adjustment of the circadian clock is an important adaptive physiological
response that allows maintenance of behavioral synchrony with solar time. Our previous …