Conservation and developmental expression of ubiquitin isopeptidases in Schistosoma mansoni

RV Pereira, HGS Vieira, VF Oliveira… - Memorias do Instituto …, 2013 - SciELO Brasil
Several genes related to the ubiquitin (Ub)-proteasome pathway, including those coding for
proteasome subunits and conjugation enzymes, are differentially expressed during the …

NEDD8 conjugation in Schistosoma mansoni: genome analysis and expression profiles

RV Pereira, MS Gomes, RP Olmo, DM Souza… - Parasitology …, 2013 - Elsevier
NEDD8 is an ubiquitin-like molecule that covalently binds to target proteins through an
enzymatic cascade analogous to ubiquitylation. This modifier is known to bind to p53 and …

Investigation on the 19S ATPase proteasome subunits (Rpt1–6) conservation and their differential gene expression in Schistosoma mansoni

OS Pereira-Júnior, RV Pereira, CS Silva… - Parasitology …, 2013 - Springer
The ubiquitin-proteasome system is responsible for degradation of the majority of
intracellular proteins in eukaryotic cells. The 26S proteasome proteolytic complex is …

Characterisation of the COP9 signalosome in Schistosoma mansoni parasites

RV Pereira, MS de Gomes, LK Jannotti-Passos… - Parasitology …, 2013 - Springer
The COP9 signalosome (CSN) is an eight-subunit complex found in all eukaryotes and
shares structural features with both the 26S proteasome 'lid'and translation factor eIF3 …

Identificação e caracterização de microRNAs de origem intrônica em Schistosoma mansoni.

VF Oliveira - 2013 - repositorio.ufop.br
microRNAs (miRNAs) são uma classe de reguladores pós-transcricionais com
aproximadamente 22 nucleotídeos. Estas moléculas regulam a expressão gênica por se …

Determinação estrutural do proteasoma 20S de Schistosoma Mansoni por modelagem comparativa.

JP Matos, J Gonçalves, A Taranto, M Junior… - BBR-Biochemistry and …, 2013 - ojs.uel.br
Proteasoma são proteínas com atividade proteolíticas sendo atrativos alvos moleculares
para o desenvolvimento de fármacos. Neste estudo, a estrutura da subunidade β1 do …