Cellular and molecular mechanisms underlying presynapse formation
PH Chia, P Li, K Shen - Journal of Cell Biology, 2013 - rupress.org
Synapse formation is a highly regulated process that requires the coordination of many cell
biological events. Decades of research have identified a long list of molecular components …
biological events. Decades of research have identified a long list of molecular components …
Interaction between autism-linked MDGAs and neuroligins suppresses inhibitory synapse development
KL Pettem, D Yokomaku, H Takahashi, Y Ge… - Journal of Cell …, 2013 - rupress.org
Rare variants in MDGAs (MAM domain–containing glycosylphosphatidylinositol anchors),
including multiple protein-truncating deletions, are linked to autism and schizophrenia, but …
including multiple protein-truncating deletions, are linked to autism and schizophrenia, but …
A matter of balance: role of neurexin and neuroligin at the synapse
ML Bang, S Owczarek - Neurochemical research, 2013 - Springer
Neurexins and neuroligins are synaptic cell adhesion molecules. Neurexins are primary
located on the presynaptic membrane, whereas neuroligins are strictly postsynaptic …
located on the presynaptic membrane, whereas neuroligins are strictly postsynaptic …
Neurexin-1β binding to neuroligin-1 triggers the preferential recruitment of PSD-95 versus gephyrin through tyrosine phosphorylation of neuroligin-1
G Giannone, M Mondin, D Grillo-Bosch, B Tessier… - Cell reports, 2013 - cell.com
Adhesion between neurexin-1β (Nrx1β) and neuroligin-1 (Nlg1) induces early recruitment of
the postsynaptic density protein 95 (PSD-95) scaffold; however, the associated signaling …
the postsynaptic density protein 95 (PSD-95) scaffold; however, the associated signaling …
The adhesion protein IgSF9b is coupled to neuroligin 2 via S-SCAM to promote inhibitory synapse development
Synaptic adhesion molecules regulate diverse aspects of synapse formation and
maintenance. Many known synaptic adhesion molecules localize at excitatory synapses …
maintenance. Many known synaptic adhesion molecules localize at excitatory synapses …
Micropatterned substrates coated with neuronal adhesion molecules for high-content study of synapse formation
K Czöndör, M Garcia, A Argento, A Constals… - Nature …, 2013 - nature.com
Studying the roles of different proteins and the mechanisms involved in synaptogenesis is
hindered by the complexity and heterogeneity of synapse types, and by the spatial and …
hindered by the complexity and heterogeneity of synapse types, and by the spatial and …
Fine mapping of loci linked to autoimmune thyroid disease identifies novel susceptibility genes
Y Tomer, A Hasham, TF Davies, M Stefan… - The Journal of …, 2013 - academic.oup.com
Context: Genetic factors play a major role in the etiology of autoimmune thyroid disease
(AITD) including Graves' disease (GD) and Hashimoto's thyroiditis (HT). We have previously …
(AITD) including Graves' disease (GD) and Hashimoto's thyroiditis (HT). We have previously …
Imaging trans-cellular neurexin-neuroligin interactions by enzymatic probe ligation
Neurexin and neuroligin are transmembrane adhesion proteins that play an important role in
organizing the neuronal synaptic cleft. Our lab previously reported a method for imaging the …
organizing the neuronal synaptic cleft. Our lab previously reported a method for imaging the …
Identification of rare copy number variants in high burden schizophrenia families
MJ Van Den Bossche, M Strazisar… - American Journal of …, 2013 - Wiley Online Library
Over the last years, genome‐wide studies consistently showed an increased burden of rare
copy number variants (CNVs) in schizophrenia patients, supporting the “common disease …
copy number variants (CNVs) in schizophrenia patients, supporting the “common disease …