Genome-wide association studies (GWASs) have enabled the discovery of common genetic
variation contributing to normal and pathological traits and clinical drug responses, but …

Numerous analyses of large patient cohorts identified specific patterns of immune activation
associated with patient survival. We established these as the immune contexture …

Background The management of metastatic breast cancer requires monitoring of the tumor
burden to determine the response to treatment, and improved biomarkers are needed …

Weighted gene coexpression network analysis (WGCNA) is a powerful 'guilt-by-association'-
based method to extract coexpressed groups of genes from large heterogeneous …

Large-scale integrated cancer genome characterization efforts including the cancer genome
atlas and the cancer cell line encyclopedia have created unprecedented opportunities to …

Summary Protein phosphatase 2A (PP2A), one of the main serine–threonine phosphatases
in mammalian cells, maintains cell homoeostasis by counteracting most of the kinase-driven …

Triple-negative breast cancers (TNBC) are aggressive with no effective targeted therapies. A
combined database analysis identified 32 inflammation-related genes differentially …

MicroRNAs (miRNAs) show differential expression across breast cancer subtypes, and have
both oncogenic and tumour-suppressive roles,,,,,. Here we report the miRNA expression …

With the emergence of individualized medicine and the increasing amount and complexity of
available medical data, a growing need exists for the development of clinical decision …

Forkhead-box (FOX) family proteins, involved in cell growth and differentiation as well as
embryogenesis and longevity, are DNA-binding proteins regulating transcription and DNA …