[HTML][HTML] The intersecting roles of endoplasmic reticulum stress, ubiquitin–proteasome system, and autophagy in the pathogenesis of proteinuric kidney disease
AV Cybulsky - Kidney international, 2013 - Elsevier
Protein misfolding in the endoplasmic reticulum (ER) leads to ER stress. The unfolded
protein response and ER-associated degradation (ERAD) interact in a coordinated manner …
protein response and ER-associated degradation (ERAD) interact in a coordinated manner …
[HTML][HTML] New insights into the pathology of podocyte loss: mitotic catastrophe
H Liapis, P Romagnani, HJ Anders - The American journal of pathology, 2013 - Elsevier
Podocytes represent an essential component of the kidney's glomerular filtration barrier.
They stay attached to the glomerular basement membrane via integrin interactions that …
They stay attached to the glomerular basement membrane via integrin interactions that …
Sestrin-2 and BNIP3 regulate autophagy and mitophagy in renal tubular cells in acute kidney injury
M Ishihara, M Urushido, K Hamada… - American Journal …, 2013 - journals.physiology.org
Autophagy is a cellular recycling process induced in response to many types of stress.
However, little is known of the signaling pathways that regulate autophagy during acute …
However, little is known of the signaling pathways that regulate autophagy during acute …
Autophagy and metabolic changes in obesity-related chronic kidney disease
J Satriano, K Sharma - Nephrology Dialysis Transplantation, 2013 - academic.oup.com
Obesity is a long-term source of cellular stress that predisposes to chronic kidney disease
(CKD). Autophagy is a homeostatic mechanism for cellular quality control through the …
(CKD). Autophagy is a homeostatic mechanism for cellular quality control through the …
Mammalian tribbles homologs at the crossroads of endoplasmic reticulum stress and Mammalian target of rapamycin pathways
R Cunard - Scientifica, 2013 - Wiley Online Library
In 2000, investigators discovered Tribbles, a Drosophila protein that coordinates
morphogenesis by inhibiting mitosis. Further work has delineated Xenopus (Xtrb2) …
morphogenesis by inhibiting mitosis. Further work has delineated Xenopus (Xtrb2) …
[PDF][PDF] 高糖通过PI3K-AKT-mTOR 信号通路增加足细胞自噬
朱吉莉， 马特安， 陈星华， 杨倩， 丁国华 - 中华肾脏病杂志, 2013 - cjn.org.cn
目的研究高糖引起足细胞自噬变化及其相关的信号机制. 方法培养的足细胞被分为6 组,
正常浓度葡萄糖(NG) 组, 高浓度葡萄糖(HG) 组, NG+ 雷帕霉素(Rap) 组, HG+ Rap 组, NG+ …
正常浓度葡萄糖(NG) 组, 高浓度葡萄糖(HG) 组, NG+ 雷帕霉素(Rap) 组, HG+ Rap 组, NG+ …
Proximal Tubules Forget “Self-Eating” When They Meet Western Meals
K Inoki - Journal of the American Society of Nephrology, 2013 - journals.lww.com
Autophagy is an evolutionarily conserved cellular catabolic process in which cytoplasmic
components are isolated from the rest of the cell within double-membrane structures …
components are isolated from the rest of the cell within double-membrane structures …
[图书][B] Autophagy: Chapter 11. The Presence of Dioxin in Kidney Cells Induces Cell Death with Autophagy
F Fiorito, L De Martino - 2013 - books.google.com
Autophagy is a cellular process of “self-eating,” which involves the digestion of cytoplasmic
components via the lysosomal pathway as resources during starvation or other limiting …
components via the lysosomal pathway as resources during starvation or other limiting …