Proinflammatory cytokines, aging, and age-related diseases

M Michaud, L Balardy, G Moulis, C Gaudin… - Journal of the American …, 2013 - Elsevier
Inflammation is a physiological process that repairs tissues in response to endogenous or
exogenous aggressions. Nevertheless, a chronic state of inflammation may have detrimental …

Caloric restriction: implications for human cardiometabolic health

CW Bales, WE Kraus - Journal of cardiopulmonary rehabilitation …, 2013 - journals.lww.com
PURPOSE: While the impact of caloric restriction on human health is not fully understood,
there is strong evidence to support further studies of its influence on cardiovascular health …

Age-associated remodeling of the intestinal epithelial barrier

L Tran… - Journals of Gerontology …, 2013 - academic.oup.com
Disorders of the gastrointestinal tract are common in the elderly people; however, the
precise trait (s) of aging that contribute to the vulnerability of the gastrointestinal tract are …

Circulating interleukin‐6 level is a prognostic marker for survival in advanced nonsmall cell lung cancer patients treated with chemotherapy

CH Chang, CF Hsiao, YM Yeh… - … journal of cancer, 2013 - Wiley Online Library
Lung cancer is the leading cause of cancer death worldwide as well as in Taiwan.
Interleukin‐6 (IL‐6) is a multifunctional cytokine and has been implicated in tumor …

Cortisol and inflammatory processes in ovarian cancer patients following primary treatment: relationships with depression, fatigue, and disability

A Schrepf, L Clevenger, D Christensen… - Brain, behavior, and …, 2013 - Elsevier
Elevations in the pro-inflammatory cytokine interleukin-6 (IL-6) and alterations in the anti-
inflammatory hormone cortisol have been reported in a variety of cancers. IL-6 has …

Relationship between systemic cytokines and complement factor H Y402H polymorphism in patients with dry age-related macular degeneration

S Cao, A Ko, M Partanen, K Pakzad-Vaezi… - American journal of …, 2013 - Elsevier
Purpose To investigate the relationship between systemic cytokines, the complement factor
H (CFH) Y402H polymorphism, drusen load, and subfoveal choroidal thickness in patients …

Identification of a metabolic signature for multidimensional impairment and mortality risk in hospitalized older patients

L Fontana, F Addante, M Copetti, G Paroni… - Aging cell, 2013 - Wiley Online Library
A combination of several metabolic and hormonal adaptations has been proposed to control
aging. Little is known regarding the effects of multiple deregulations of these metabolic and …

Effect of age on atherogenicity of LDL and inflammatory markers in healthy women

JK Paik, JS Chae, R Kang, N Kwon, SH Lee… - Nutrition, Metabolism and …, 2013 - Elsevier
Background and aim Since using LDL level alone is insufficient as a method to identify
individuals with incident coronary artery disease (CAD), other factors may be implicated in …

Septic shock in older people: a prospective cohort study

F Pinheiro da Silva, FG Zampieri, DF Barbeiro… - Immunity & …, 2013 - Springer
Background Septic shock is the first cause of death in Intensive Care Units. Despite
experimental data showing increased inflammatory response of aged animals following …

Aging, nutrient signaling, hematopoietic senescence, and cancer

P Balasubramanian, VD Longo - Critical Reviews™ in …, 2013 - dl.begellhouse.com
It is well known that cancer is one of the main causes of mortality in the aged population.
Recent studies suggest that oncogenic pathways, such as the insulin-like growth factor-1 …