Recently we reported the synthesis and structure–activity study of endomorphin-1 (EM-1)
analogues containing novel, unnatural α-methylene-β-aminopropanoic acids (Map). In the …

This study reports on new pharmacologically active endomorphin-2 analogues,
incorporating β 2-hPhe, β 3-hPhe and β 3-hTic unnatural amino acids in the place of the Phe …

A highly efficient one‐pot synthesis of some new spiro‐2‐aminopyrimidinones via a three‐
component reaction of cyclic ketones, methylcyanoacetate or malononitrile, and …

A highly efficient of some new spiro-2-aminopyrimidinones via a three-component reaction
of cyclic ketones, methylcyanoacetate or malononitrile, and guanidinium carbonate has …

This Ph. D. thesis is located in the medicinal chemistry research field. Peptides are among
the most studied entities as potential drug candidates, due to their natural abundance and …