Synthesis and study of benzothiazole conjugates in the control of cell proliferation by modulating Ras/MEK/ERK-dependent pathway in MCF-7 cells

A Kamal, S Faazil, MJ Ramaiah, M Ashraf… - Bioorganic & medicinal …, 2013 - Elsevier
By applying a methodology, a series of benzothiazole–pyrrole based conjugates (4a–r)
were synthesized and evaluated for their antiproliferative activity. Compounds such as 4a …

Ethynyl-substituted pyridine and pyrimidine derivatives and their use in treating viral infections

CD Kwong, FG Njoroge, S Ananthan… - US Patent …, 2013 - Google Patents
2009-11-05 Assigned to SOUTHERN RESEARCH INSTITUTE reassignment SOUTHERN
RESEARCH INSTITUTE ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …

AZO-substituted pyridine and pyrimidine derivatives and their use in treating viral infections

CD Kwong, FG Njoroge, S Ananthan, F Geng… - US Patent …, 2013 - Google Patents
FR 2574407 A1 6, 1986 JP 49-26295* 3/1974 WO 93.1702 O A2 9, 1993 WO 98.14181 A1
4f1998 WO 98.17679 A1 4f1998 WO 98.22496 A2 5, 1998 WO 99.07734 A2 2, 1999 WO …

[HTML][HTML] A chemical biology strategy to analyze rheostat-like protein kinase-dependent regulation

SA Kawashima, A Takemoto, P Nurse, TM Kapoor - Chemistry & biology, 2013 - cell.com
Protein kinases may function more like variable rheostats rather than two-state switches.
However, we lack approaches to properly analyze this aspect of kinase-dependent …

[HTML][HTML] Rheostat-ing Mitosis

PA Eyers - Chemistry & Biology, 2013 - cell.com
Ark1, the unique Aurora kinase in Schizosaccharomyces pombe, regulates multiple aspects
of mitosis. In this issue of Chemistry & Biology, Kawashima and colleagues report the …