Updated international consensus guidelines on the management of cytomegalovirus in solid-organ transplantation

CN Kotton, D Kumar, AM Caliendo, A Åsberg… - …, 2013 - journals.lww.com
Cytomegalovirus (CMV) continues to be one of the most common infections after solid-organ
transplantation, resulting in significant morbidity, graft loss, and adverse outcomes …

[HTML][HTML] Pretransplant immediately early-1-specific T cell responses provide protection for CMV infection after kidney transplantation

O Bestard, M Lucia, E Crespo, B Van Liempt… - American Journal of …, 2013 - Elsevier
Cytomegalovirus (CMV) infection is still a major complication after kidney transplantation.
Although cytotoxic CMV-specific T cells play a crucial role controlling CMV survival and …

An international multicenter performance analysis of cytomegalovirus load tests

HH Hirsch, I Lautenschlager, BA Pinsky… - Clinical infectious …, 2013 - academic.oup.com
Background. Quantification of cytomegalovirus (CMV) load is central to the management of
CMV infections in immunocompromised patients, but quantitative results currently differ …

Virologic suppression measured by a cytomegalovirus (CMV) DNA test calibrated to the World Health Organization international standard is predictive of CMV disease …

RR Razonable, A Åsberg, H Rollag… - Clinical infectious …, 2013 - academic.oup.com
Background. Cytomegalovirus (CMV) load measurement is used to assess the efficacy of
treatment of CMV disease, but lacks standardization. Using the World Health Organization …

Determination, validation and standardization of a CMV DNA cut-off value in plasma for preemptive treatment of CMV infection in solid organ transplant recipients at …

C Martin-Gandul, P Pérez-Romero, M Sánchez… - Journal of clinical …, 2013 - Elsevier
BACKGROUND: Valganciclovir preemptive therapy guided by the viral load is the current
strategy recommended for preventing CMV disease in CMV-seropositive Solid Organ …

Valganciclovir: therapeutic role in pediatric solid organ transplant recipients

MA Yu, JM Park - Expert opinion on pharmacotherapy, 2013 - Taylor & Francis
Introduction: Cytomegalovirus (CMV) infection is a common infectious complication after
solid organ transplantation (SOT) and is associated with the increased risk of opportunistic …

Cytomegalovirus infection post‐pancreas–kidney transplantation–results of antiviral prophylaxis in high‐risk patients

SM Fallatah, MA Marquez, F Bazerbachi… - Clinical …, 2013 - Wiley Online Library
Background Cytomegalovirus (CMV) is a major pathogen affecting solid organ transplant
(SOT) recipients. Prophylactic strategies have decreased the rate of CMV infection/disease …

Editorial Commentary: The Long Road Toward Standardization of Viral Load Testing for Cytomegalovirus

AM Caliendo - Clinical infectious diseases, 2013 - academic.oup.com
Applying molecular methods to the detection and quantification of cytomegalovirus (CMV)
DNA in transplant recipients has been much more challenging than expected. After 20 …

Six-month low-dose valganciclovir prophylaxis in cytomegalovirus D+/R− kidney transplant patients receiving thymoglobulin induction

FL Luan - Transplantation Proceedings, 2013 - Elsevier
BACKGROUND: The use of T-cell-depleting antibody, such as thymoglobulin, is a risk factor
for cytomegalovirus (CMV) infection. We studied the effectiveness of 6 months of low-dose …

Clinical outcome with low-dose valacyclovir in high-risk renal transplant recipients: a 10-year experience

F Sund, G Tufveson, B Döhler, G Opelz… - Nephrology Dialysis …, 2013 - academic.oup.com
Background Cytomegalovirus (CMV) remains an important pathogen in transplant patients,
and valacyclovir (VACV) prophylaxis 8 g/day has been used in high-risk CMV …