Results of epidemiological studies have shown that chronic obstructive pulmonary disease
(COPD) is frequently associated with comorbidities, the most serious and prevalent being …

Lung cancer is a leading cause of cancer death and disease burden in many countries.
Understanding of the biological pathways involved in lung cancer aetiology is required to …

TERT-locus SNPs and leukocyte telomere measures are reportedly associated with risks of
multiple cancers. Using the Illumina custom genotyping array iCOGs, we analyzed∼ 480 …

We consider in this paper testing for interactions between a genetic marker set and an
environmental variable. A common practice in studying gene–environment (GE) interactions …

Lung cancer is one of the most common and deadliest cancers in the world. The major socio-
environmental risk factor involved in the development of lung cancer is cigarette smoking …

BACKGROUND: CYP1A1, CYP2A6 and CHRNA5 are biologically plausible genes as risk
factors for lung cancer but no studies have been reported in the Bangladeshi population …

Lung cancer is the leading cause of cancer death worldwide in part due to our inability to
identify which smokers are at highest risk and the lack of effective tools to detect the disease …

We know that cigarette smoking is a leading preventable cause of carcinogenesis in lung
cancer. Cigarette smoke is a mixture of more than 5000 chemical compounds, among which …

Genetic studies have shown an association between single-nucleotide polymorphisms on
chromosome 15q25 and smoking-related traits and diseases, such as quantity of smoking …

Telomeres are DNA-protein structures that cap the ends of chromosomes; telomerase is the
enzyme that ensures their integrity. Telomere biology has recently been implicated in the …