The deleterious effects of chronic stress on health and its contribution to the development of
mental illness attract broad attention worldwide. An important development in the last few …

It has long been established in traditional forms of medicine and in anecdotal knowledge
that the health of the body and the mind are inextricably linked. Strong and continually …

Exposure to maternal anxiety predicts offspring brain development. However, because
children's brains are commonly assessed years after birth, the timing of such maternal …

Introduction Depression and anxiety disorders have been associated with hyperactivity of
the hypothalamic-pituitary adrenal (HPA) axis. However, lower cortisol levels have also …

CONTEXT: The hypothalamic-pituitary-adrenal (HPA) axis is one of the body's main systems
that controls response to stress. It acts through the hormone cortisol. While the dysregulation …

BACKGROUND: Dyslipidemia and obesity have been observed in persons with severe
anxiety or depression, and in tricyclic antidepressant (TCA) users. This likely contributes to …

Anxiety and depressive problems have often been related to higher hypothalamic–pituitary–
adrenal (HPA)-axis activity (basal morning cortisol levels and cortisol awakening response …

This study used a stress biomarker, diurnal cortisol, to identify how elevated stress in
mothers of children and adults with autism and other disabilities relates to their health and …

BACKGROUND: The hypothalamus is a brain structure involved in the neuroendocrine
aspect of stress and anxiety. Evidence suggests that generalized anxiety disorder (GAD) …

Preliminary study in our laboratory showed that etazolate produced antidepressant-and
anxiolytic-like effects in rodent models, however, the ability of etazolate to produce …