Mechanisms of immune modulation by mesenchymal stromal cells and clinical translation

J Stagg, J Galipeau - Current molecular medicine, 2013 - ingentaconnect.com
Cell therapy with mesenchymal stromal cells (MSCs) is the focus of intensive investigation.
Several clinical trials, including large-scale placebo-controlled phase III clinical trials, are …

MSC and tumors: homing, differentiation, and secretion influence therapeutic potential

N D'souza, JS Burns, G Grisendi, O Candini… - … Stem Cells-Basics and …, 2013 - Springer
Mesenchymal stromal/stem cells (MSC) are adult multipotent progenitors with fibroblast-like
morphology able to differentiate into adipocytic, osteogenic, chondrogenic, and myogenic …

Human umbilical cord mesenchymal stem cells as vehicles of CD20-specific TRAIL fusion protein delivery: a double-target therapy against non-Hodgkin's lymphoma

C Yan, S Li, Z Li, H Peng, X Yuan, L Jiang… - Molecular …, 2013 - ACS Publications
Mesenchymal stem cells (MSCs) are an attractive candidate for cell-based therapy. We have
designed a promising double-target therapeutic system for non-Hodgkin's lymphoma (NHL) …

PRAME/EZH2-mediated regulation of TRAIL: a new target for cancer therapy

DD De Carvalho, BP Mello… - Current Molecular …, 2013 - ingentaconnect.com
The tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) exerts a cancer cell-
specific pro-apoptotic activity. This property made the TRAIL associated pathway one of the …

TRAIL-based therapeutic approaches for the treatment of pediatric malignancies

C Gasparini, L Vecchi Brumatti… - Current medicinal …, 2013 - ingentaconnect.com
Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) is a pro-apoptotic ligand
that has shown the exquisite ability to trigger extrinsic apoptosis in various types of cancer …

Mesenchymal stem cells: a revolution in therapeutic strategies of age-related diseases

Y Peng, S Huang, B Cheng, X Nie, J Enhe… - Ageing research …, 2013 - Elsevier
The great evolutionary biologist Theodosius Dobzhansky once said:“Nothing in biology
makes sense except in the light of evolution”. Aging is a complex biological phenomenon …

Genetically Engineered Mesenchymal Stem Cells for Cell and Gene Therapy

Y Jung, JA Nolta - Mesenchymal Stem Cell Therapy, 2013 - Springer
Stem cells have enormous potential for regenerative medicine to treat fatal diseases and
injuries that cannot otherwise be healed. In particular, adult stem cell-based therapies have …

[引用][C] 干细胞与糖尿病肾病

杨光, 程庆砾 - 北京大学学报: 医学版, 2013