Cancers develop in complex tissue environments, which they depend on for sustained
growth, invasion and metastasis. Unlike tumor cells, stromal cell types within the tumor …

How cancer cells acquire the competence to colonize distant organs remains a central
question in cancer biology. Tumors can release large numbers of cancer cells into the …

Emotional stress activates the sympathetic nervous system (SNS) and release of the
neurotransmitter norepinephrine to promote breast tumor pathogenesis. We demonstrate …

The role of the perioperative period during cancer surgery and its impact on patients' long-
term cancer outcomes are of increasing interest. Anticipation and prevention of perioperative …

In a significant translational study, Magnon et al. investigated the role that the autonomic
nervous system plays in the development and spread of prostate cancer in both mice and …

The functions of the autonomic nervous system have expanded in the last years from 'fight-or-
flight'responses to fine-tuned control of multiple homeostatic and pathological processes …

In a study recently published in Science, Magnon et al. show that both the sympathetic and
parasympathetic components of the autonomic nervous system play an integral part in the …

The progression of cancer is supported by a wide variety of non-neoplastic cell types which
make up the tumour stroma, including immune cells, endothelial cells, cancer-associated …

Systems biology is a recent addition to the necessary but insufficient reductionist approach
used in biological research. Systems biology is focused on understanding living things as a …

Einstein College of Medicine, the Mount Sinai School of Medicine, the Durham VA Medical
Centre and Duke University published an elegant study demonstrating that the sympathetic …