Cells use messenger RNAs (mRNAs) to ensure the accurate dissemination of genetic
information encoded by DNA. Given that mRNAs largely direct the synthesis of a critical …

The nonsense-mediated mRNA decay (NMD) pathway is well known as a translation-
coupled quality control system that recognizes and degrades aberrant mRNAs with …

Nonsense-mediated mRNA decay (NMD) is a eukaryotic post-transcriptional gene
regulation mechanism that eliminates mRNAs with the termination codon (TC) located in an …

Nonsense-mediated mRNA decay (NMD) is an mRNA quality control mechanism that
destabilizes aberrant mRNAs harboring premature termination (nonsense) codons (PTCs) …

SMG‐1, a member of the PIKK (phosphoinositide 3‐kinase‐related kinase) family, plays a
critical role in the m RNA quality control system known as nonsense‐mediated m RNA …

We report a new mechanism by which human mRNAs cross-talk: an Alu element in the 3′
untranslated region (3′ UTR) of one mRNA can base-pair with a partially complementary …

Mental retardation (MR) is a group of common and complex disabilities affecting the central
nervous system and appears before the period of brain developmental maturity. Recently …

Abstract Staufen1 (STAU1) is a double-stranded RNA-binding protein. In mammals, STAU1
binding to the 3'-untranslated region (3'UTR) of mRNAs that contain a STAU1-binding site …

Der” Nonsense-mediated mRNA Decay “(NMD) ist ein Mechanismus zur
translationsabhängigen mRNA-Überwachung in Eukaryonten: er degradiert mRNAs mit …

Nonsense-mediated mRNA decay (NMD) is a quality control mechanism that detects and
rapidly degrades mRNAs carrying premature translation-termination codons (PTCs) …