Primary myelofibrosis: 2013 update on diagnosis, risk‐stratification, and management

A Tefferi - American journal of hematology, 2013 - Wiley Online Library
Disease overview Primary myelofibrosis (PMF) is a myeloproliferative neoplasm
characterized by stem cell‐derived clonal myeloproliferation, abnormal cytokine expression …

The role of JAK pathway dysregulation in the pathogenesis and treatment of acute myeloid leukemia

HJ Lee, N Daver, HM Kantarjian, S Verstovsek… - Clinical Cancer …, 2013 - AACR
The discovery of the Janus kinase 2 (JAK2) V617F mutation has improved our
understanding of the pathophysiology of myeloproliferative neoplasms such as …

Treatment outcomes following leukemic transformation in Philadelphia-negative myeloproliferative neoplasms

JA Kennedy, EG Atenafu, HA Messner… - Blood, The Journal …, 2013 - ashpublications.org
Leukemic transformation (LT) is a rare but fatal complication of Philadelphia-negative
myeloproliferative neoplasms (MPNs) for which optimal treatment strategies are not known …

[HTML][HTML] Федеральные клинические рекомендации по диагностике и терапии хронического миелолейкоза

КМ Абдулкадыров, АО Абдуллаев… - Вестник …, 2013 - cyberleninka.ru
Хронический миелолейкоз (ХМЛ)—редкое заболевание, число впервые выявленных
больных которым в год составляет приблизительно 1: 100 000 населения. В …

Interferon α may be back on track to treat acute myeloid leukemia

ELJM Smits, S Anguille, ZN Berneman - Oncoimmunology, 2013 - Taylor & Francis
Our own experience and a thorough literature review suggest that interferon α (IFNα) should
be reconsidered for the treatment of acute myeloid leukemia patients. Most likely, the …

Practical management of patients with myelofibrosis receiving ruxolitinib

C Harrison, R Mesa, D Ross, A Mead… - Expert review of …, 2013 - Taylor & Francis
Myelofibrosis (MF) is characterized by bone marrow fibrosis, progressive anemia and
extramedullary hematopoiesis, primarily manifested as splenomegaly. Patients also …

Prognostic model to identify patients with myelofibrosis at the highest risk of transformation to acute myeloid leukemia

A Quintás-Cardama, H Kantarjian, S Pierce… - … Myeloma and Leukemia, 2013 - Elsevier
Background Some patients with myelofibrosis (MF) progress to acute myeloid leukemia
(AML). Current prognostic tools were not devised to assess risk of AML transformation …

Acute myeloid leukemia following a myeloproliferative neoplasm: clinical characteristics, genetic features and effects of therapy

ML Heaney, G Soriano - Current hematologic malignancy reports, 2013 - Springer
Acute myeloid leukemia (AML) is an uncommon, but often deadly complication of
myeloproliferative neoplasms (MPN). Post-MPN AML usually occurs years after the initial …

Genetic basis of MPN: beyond JAK2-V617F

NCC Them, R Kralovics - Current hematologic malignancy reports, 2013 - Springer
The clonal blood disorders polycythemia vera, essential thrombocythemia and primary
myelofibrosis belong to the BCR-ABL1-negative myeloproliferative neoplasms and are …

[HTML][HTML] Критерии диагностики и современные методы лечения первичного миелофиброза

КМ Абдулкадыров, ВА Шуваев… - Вестник …, 2013 - cyberleninka.ru
Первичный миелофиброз (ПМФ)—редкое заболевание, число впервые выявленных
больных которым в год составляет приблизительно 1: 100 000 населения. Синонимы …