Comparative effectiveness of treatments for open-angle glaucoma: a systematic review for the US Preventive Services Task Force
Background: Glaucoma is an acquired degeneration of the optic nerve and a leading cause
of blindness worldwide. Medical and surgical treatments that decrease intraocular pressure …
of blindness worldwide. Medical and surgical treatments that decrease intraocular pressure …
[HTML][HTML] Glaucoma: a disease of early cellular senescence
J Caprioli - Investigative ophthalmology & visual science, 2013 - jov.arvojournals.org
This review examines glaucoma as a disease of early cellular senescence. There is ample
evidence for this position, for both the anterior and the posterior ocular segments. The …
evidence for this position, for both the anterior and the posterior ocular segments. The …
[HTML][HTML] Soluble Guanylate Cyclase α1–Deficient Mice: A Novel Murine Model for Primary Open Angle Glaucoma
Primary open angle glaucoma (POAG) is a leading cause of blindness worldwide. The
molecular signaling involved in the pathogenesis of POAG remains unknown. Here, we …
molecular signaling involved in the pathogenesis of POAG remains unknown. Here, we …
Neuroprotection in glaucoma: present and future
Neuroprotection in glaucoma: present and future : Chinese Medical Journal
Neuroprotection in glaucoma: present and future : Chinese Medical Journal Log in or …
Neuroprotection in glaucoma: present and future : Chinese Medical Journal Log in or …
Solving the lost in translation problem: improving the effectiveness of translational research
C Ergorul, LA Levin - Current opinion in pharmacology, 2013 - Elsevier
Translational research frequently fails to replicate in the clinic what has been demonstrated
in the laboratory. This has been true for neuroprotection in the central nervous system …
in the laboratory. This has been true for neuroprotection in the central nervous system …
Critical assessment of implantable drug delivery devices in glaucoma management
D Manickavasagam, MO Oyewumi - Journal of drug delivery, 2013 - Wiley Online Library
Glaucoma is a group of heterogeneous disorders involving progressive optic neuropathy
that can culminate into visual impairment and irreversible blindness. Effective therapeutic …
that can culminate into visual impairment and irreversible blindness. Effective therapeutic …
Neuroprotection of medical IOP-lowering therapy
N Pfeiffer, J Lamparter, A Gericke, FH Grus… - Cell and tissue …, 2013 - Springer
Intraocular pressure (IOP)-lowering therapy has been shown to arrest or retard the
progression of optic neuropathy typical for glaucoma and can, thus, be described as …
progression of optic neuropathy typical for glaucoma and can, thus, be described as …
[HTML][HTML] New trends in glaucoma risk, diagnosis & management
T Kersey, CI Clement, P Bloom… - Indian Journal of …, 2013 - journals.lww.com
Recent advances have seen a surge of new ideas and technologies to aid in the detection,
treatment and further understanding of glaucoma. These technologies and advances are …
treatment and further understanding of glaucoma. These technologies and advances are …
Clinical update on normal tension glaucoma
RC Mudumbai - Seminars in ophthalmology, 2013 - Taylor & Francis
Normal tension glaucoma (NTG) is a common form of open-angle glaucoma that can lead to
significant visual morbidity. There has been considerable debate as to whether NTG fits …
significant visual morbidity. There has been considerable debate as to whether NTG fits …
Melatonin and its analog 5-methoxycarbonylamino-N-acetyltryptamine potentiate adrenergic receptor-mediated ocular hypotensive effects in rabbits: significance for …
A Crooke, F Huete-Toral, A Martínez-Águila… - … of Pharmacology and …, 2013 - ASPET
Melatonin is currently considered a promising drug for glaucoma treatment because of its
ocular hypotensive and neuroprotective effects. We have investigated the effect of melatonin …
ocular hypotensive and neuroprotective effects. We have investigated the effect of melatonin …