Cancer stem cells (CSCs) or tumor initiating cells (TICs) contribute to tumorigenesis,
metastasis, recurrence and chemoresistance. CD133, a pentaspan membrane glycoprotein …

The cancer stem cell (CSC) hypothesis, despite the limitations of the currently available
models and assays, has ushered in a new era of excitement in cancer research. The …

The biological significance of a known normal and cancer stem cell marker CD133 remains
elusive. We now demonstrate that the phosphorylation of tyrosine-828 residue in CD133 C …

Cancer is a heterogeneous disease, which provides a broad field for investigation, while
simultaneously reducing the chances for a universal treatment. Malignant gliomas are the …

Expression of the membrane protein CD133 marks a subset of cancer cells with drug
resistant phenotype and enhanced tumor initiating ability in xenotransplantation assays …

Despite medical advances made over the past decade, ovarian cancer remains one of the
more lethal gynecologic cancers in the United States. While current therapeutic strategies …

Abstract CD133 (prominin-1) is a member of the transmembrane glycoprotein family and
was initially described as a specific marker to select human hematopoietic progenitor cells …

Exosomes can be viewed as complex “messages” packaged to survive trips to other cells in
the local microenvironment and, through body fluids, to distant sites. A large body of …

Objective To investigate the correlation between CD133-positive gastric cancer and
clinicopathological features and its impact on survival. Methods A search in the Medline and …

The neocortex, the evolutionarily newest part of the cerebral cortex, controls nearly all
aspects of behavior, including perception, language, and decision making. It contains an …