Acute lymphoblastic leukaemia
H Inaba, M Greaves, CG Mullighan - The Lancet, 2013 - thelancet.com
Acute lymphoblastic leukaemia occurs in both children and adults but its incidence peaks
between 2 and 5 years of age. Causation is multifactorial and exogenous or endogenous …
between 2 and 5 years of age. Causation is multifactorial and exogenous or endogenous …
JAKs and STATs in immunity, immunodeficiency, and cancer
JAKs and STATs in Immunity, Immunodeficiency, and Cancer | NEJM Skip to main content
NEJM Group Follow Us Facebook Twitter Instagram YouTube LinkedIn Prepare to become a …
NEJM Group Follow Us Facebook Twitter Instagram YouTube LinkedIn Prepare to become a …
JAK/STAT signaling in hematological malignancies
W Vainchenker, SN Constantinescu - Oncogene, 2013 - nature.com
The Janus kinase (JAK)/signal transducer and activator of transcription (STAT) pathway is
central to signaling by cytokine receptors, a superfamily of more than 30 transmembrane …
central to signaling by cytokine receptors, a superfamily of more than 30 transmembrane …
Independent prognostic value of BCR-ABL1-like signature and IKZF1 deletion, but not high CRLF2 expression, in children with B-cell precursor ALL
A Van der Veer, E Waanders, R Pieters… - Blood, The Journal …, 2013 - ashpublications.org
Most relapses in childhood B-cell precursor acute lymphoblastic leukemia (BCP-ALL) are
not predicted using current prognostic features. Here, we determined the co-occurrence and …
not predicted using current prognostic features. Here, we determined the co-occurrence and …
The biology of thymic stromal lymphopoietin (TSLP)
SF Ziegler, F Roan, BD Bell, TA Stoklasek… - Advances in …, 2013 - Elsevier
Originally shown to promote the growth and activation of B cells, thymic stromal
lymphopoietin (TSLP) is now known to have wide-ranging impacts on both hematopoietic …
lymphopoietin (TSLP) is now known to have wide-ranging impacts on both hematopoietic …
Children's Oncology Group's 2013 blueprint for research: acute lymphoblastic leukemia
Abstract Approximately 90% of the 2,000 children, adolescents, and young adults enrolled
each year in Children's Oncology Group acute lymphoblastic leukemia (ALL) trials will be …
each year in Children's Oncology Group acute lymphoblastic leukemia (ALL) trials will be …
[HTML][HTML] IKZF1 deletion is an independent predictor of outcome in pediatric acute lymphoblastic leukemia treated according to the ALL-BFM 2000 protocol
P Dörge, B Meissner, M Zimmermann, A Möricke… - …, 2013 - ncbi.nlm.nih.gov
IKZF1 gene deletions have been associated with a poor outcome in pediatric precursor B-
cell acute lymphoblastic leukemia. To assess the prognostic relevance of IKZF1 deletions for …
cell acute lymphoblastic leukemia. To assess the prognostic relevance of IKZF1 deletions for …
[HTML][HTML] Genes commonly deleted in childhood B-cell precursor acute lymphoblastic leukemia: association with cytogenetics and clinical features
In childhood B-cell precursor acute lymphoblastic leukemia, cytogenetics is important in
diagnosis and as an indicator of response to therapy, thus playing a key role in risk …
diagnosis and as an indicator of response to therapy, thus playing a key role in risk …
[HTML][HTML] Integrated genetic and epigenetic analysis of childhood acute lymphoblastic leukemia
ME Figueroa, SC Chen, AK Andersson… - The Journal of …, 2013 - Am Soc Clin Investig
Acute lymphoblastic leukemia (ALL) is the commonest childhood malignancy and is
characterized by recurring structural genetic alterations. Previous studies of DNA …
characterized by recurring structural genetic alterations. Previous studies of DNA …
Predicting relapse risk in childhood acute lymphoblastic leukaemia
DT Teachey, SP Hunger - British journal of haematology, 2013 - Wiley Online Library
Intensive multi‐agent chemotherapy regimens and the introduction of risk‐stratified therapy
have substantially improved cure rates for children with acute lymphoblastic leukaemia …
have substantially improved cure rates for children with acute lymphoblastic leukaemia …