Megestrol acetate for treatment of anorexia‐cachexia syndrome

VR Garcia, E López‐Briz, RC Sanchis… - Cochrane Database …, 2013 - cochranelibrary.com
Background This is an updated version of a previously published review in The Cochrane
Library (2005, Issue 2) on'Megestrol acetate for the treatment of anorexia‐cachexia …

Understanding, recognizing, and managing toxicities of targeted anticancer therapies

GK Dy, AA Adjei - CA: a cancer journal for clinicians, 2013 - Wiley Online Library
Answer questions and earn CME/CNE Advances in genomics and molecular biology have
identified aberrant proteins in cancer cells that are attractive targets for cancer therapy …

Cancer cachexia—pathophysiology and management

H Suzuki, A Asakawa, H Amitani, N Nakamura… - Journal of …, 2013 - Springer
About half of all cancer patients show a syndrome of cachexia, characterized by anorexia
and loss of adipose tissue and skeletal muscle mass. Cachexia can have a profound impact …

Malnutrition, anorexia and cachexia in cancer patients: a mini-review on pathogenesis and treatment

A Nicolini, P Ferrari, MC Masoni, M Fini… - Biomedicine & …, 2013 - Elsevier
Malnutrition, anorexia and cachexia are a common finding in cancer patients. They become
more evident with tumor growth and spread. However, the mechanisms by which they are …

Complementary therapies and integrative medicine in lung cancer: diagnosis and management of lung cancer: American College of Chest Physicians evidence …

GE Deng, SM Rausch, LW Jones, A Gulati, NB Kumar… - Chest, 2013 - Elsevier
Background Physicians are often asked about complementary therapies by patients with
cancer, and data show that the interest in and use of these therapies among patients with …

HDL and Glut1 inhibition reverse a hypermetabolic state in mouse models of myeloproliferative disorders

EL Gautier, M Westerterp, N Bhagwat… - Journal of Experimental …, 2013 - rupress.org
A high metabolic rate in myeloproliferative disorders is a common complication of
neoplasms, but the underlying mechanisms are incompletely understood. Using three …

Effect of colon cancer and surgical resection on skeletal muscle mitochondrial enzyme activity in colon cancer patients: a pilot study

BE Phillips, K Smith, S Liptrot, PJ Atherton… - Journal of cachexia …, 2013 - Springer
Background Colon cancer (CC) patients commonly suffer declines in muscle mass and
aerobic function. We hypothesised that CC would be associated with reduced muscle mass …

Comparison of three different treatment modalities in the management of cancer cachexia

O Kanat, E Cubukcu, N Avci, F Budak, I Ercan… - Tumori …, 2013 - journals.sagepub.com
Aims and background The optimal treatment of cancer cachexia remains unknown. In this
study, we compared the efficacy of three different treatment modalities in the management of …

TNF‐α and IFN‐s‐Dependent Muscle Decay Is Linked to NF‐κB‐ and STAT‐1α‐Stimulated Atrogin1 and MuRF1 Genes in C2C12 Myotubes

B Pijet, M Pijet, A Litwiniuk, M Gajewska… - Mediators of …, 2013 - Wiley Online Library
TNF‐α was shown to stimulate mitogenicity in C2C12 myoblasts. Selected cytokines TNF‐α,
IFNα, or IFNγ reduced the expression of myosin heavy chain (MyHC IIa) when given …

Anti-diabetic action of 7-O-galloyl-D-sedoheptulose, a polyphenol from Corni Fructus, through ameliorating inflammation and inflammation-related oxidative stress in …

CH Park, T Tanaka, T Yokozawa - Biological and Pharmaceutical …, 2013 - jstage.jst.go.jp
Compelling evidence indicates that polyphenolic antioxidants show protective effects
against diabetic complications. We investigated the effects of a polyphenolic compound, 7-O …