New directions in antiarrhythmic drug therapy for atrial fibrillation
Atrial fibrillation (AF) is the most prevalent cardiac arrhythmia and has a significant impact on
morbidity and mortality. Current antiarrhythmic drugs for AF suffer from limited safety and …
morbidity and mortality. Current antiarrhythmic drugs for AF suffer from limited safety and …
Mutation E169K in junctophilin-2 causes atrial fibrillation due to impaired RyR2 stabilization
Objectives: This study sought to study the role of junctophilin-2 (JPH2) in atrial fibrillation
(AF). Background: JPH2 is believed to have an important role in sarcoplasmic reticulum (SR) …
(AF). Background: JPH2 is believed to have an important role in sarcoplasmic reticulum (SR) …
Transmural conduction is the predominant mechanism of breakthrough during atrial fibrillation: evidence from simultaneous endo-epicardial high-density activation …
J Eckstein, S Zeemering, D Linz, B Maesen… - Circulation …, 2013 - Am Heart Assoc
Background—Endo-epicardial dissociation (EED) of electric activations resulting in
transmural conduction of fibrillation waves (breakthroughs) has been postulated to …
transmural conduction of fibrillation waves (breakthroughs) has been postulated to …
Sevoflurane Protects Ventricular Myocytes against Oxidative Stress-induced Cellular Ca2+ Overload and Hypercontracture
A Kojima, H Kitagawa, M Omatsu-Kanbe… - …, 2013 - pubs.asahq.org
Background: Oxidative stress is implicated in pathogenesis of cardiac reperfusion injury,
characterized by cellular Ca2+ overload and hypercontracture. Volatile anesthetics protect …
characterized by cellular Ca2+ overload and hypercontracture. Volatile anesthetics protect …
S4153R is a gain-of-function mutation in the cardiac Ca2+ release channel ryanodine receptor associated with catecholaminergic polymorphic ventricular tachycardia …
P Zhabyeyev, F Hiess, R Wang, Y Liu… - Canadian Journal of …, 2013 - Elsevier
Mutations in ryanodine receptor 2 (RYR2) gene can cause catecholaminergic polymorphic
ventricular tachycardia (CPVT). The novel RYR2-S4153R mutation has been implicated as a …
ventricular tachycardia (CPVT). The novel RYR2-S4153R mutation has been implicated as a …
Fibrilación auricular y flutter auricular
NC Galiano, I García-Bolao - Medicine-Programa de Formación Médica …, 2013 - Elsevier
Atrial fibrillation and atrial flutterAtrial fibrillation is the most common arrhythmia in clinical
practice. It affects 1-2% of the general population and it is estimated that this prevalence will …
practice. It affects 1-2% of the general population and it is estimated that this prevalence will …
Recent advances in antiarrhythmic drug treatment of atrial fibrillation
MM Polovina, TS Potpara - Recent Patents on Cardiovascular …, 2013 - ingentaconnect.com
Atrial fibrillation (AF) is the most prevalent sustained cardiac arrhythmia in clinical practice
associated with significant morbidity and mortality. With the growing number of the affected …
associated with significant morbidity and mortality. With the growing number of the affected …
[图书][B] The Role of MicroRNA Regulation of Cardiac Ion Channel in Arrhythmia
X Luo - 2013 - search.proquest.com
Atrial fibrillation (AF) is the most frequently-encountered arrhythmia in clinical practice and
constitutes a major cause of cardiac morbidity and mortality. The management of AF remains …
constitutes a major cause of cardiac morbidity and mortality. The management of AF remains …
Mechanisms of Action of Antiarrhythmic Drugs in Atrial Fibrillation
A Burashnikov, C Antzelevitch - Electrical Diseases of the Heart: Volume 1 …, 2013 - Springer
The principal goal of antiarrhythmic therapy in the management of atrial fibrillation (AF) is to
prolong the effective refractory period (ERP), which makes rapid activation of the atria …
prolong the effective refractory period (ERP), which makes rapid activation of the atria …
[PDF][PDF] Transmural Conduction Is the Predominant Mechanism of Breakthrough During Atrial Fibrillation
EFSEE High - 2013 - scholar.archive.org
Background—Endo-epicardial dissociation (EED) of electric activations resulting in
transmural conduction of fibrillation waves (breakthroughs) has been postulated to …
transmural conduction of fibrillation waves (breakthroughs) has been postulated to …