Nowadays, mass spectrometry‐based proteomics is carried out primarily in a bottom‐up
fashion, with peptides obtained after proteolytic digest of a whole proteome lysate as the …

Proteins play a fundamental role in establishing the diversity of cellular processes in health
or disease systems. This diversity is accomplished by a vast array of protein functions. In …

The analysis of exonic DNA from prostate cancers has identified recurrently mutated genes,
but the spectrum of genome-wide alterations has not been profiled extensively in this …

The incidence of esophageal adenocarcinoma (EAC) has risen 600% over the last 30 years.
With a 5-year survival rate of∼ 15%, the identification of new therapeutic targets for EAC is …

Ribosomal RNA genes have become the standard molecular markers for microbial
community analysis for good reasons, including universal occurrence in cellular organisms …

Abstract The Protein Model Portal (PMP) has been developed to foster effective use of 3D
molecular models in biomedical research by providing convenient and comprehensive …

We evaluated the presence/absence of proteins encoded by 14 077 genes in adipocytes
obtained from different tissue samples using immunohistochemistry. By combining this with …

We have developed a specialized database, HBVdb (http://hbvdb. ibcp. fr), allowing the
researchers to investigate the genetic variability of Hepatitis B Virus (HBV) and viral …

During protein synthesis, tRNAs move from the ribosome's aminoacyl to peptidyl to exit sites.
Here we investigate conformational motions during spontaneous translocation, using …

Abstract The Gene Ontology Consortium (GOC) is a community-based bioinformatics project
that classifies gene product function through the use of structured controlled vocabularies. A …