The clinical relevance of the interaction between human cancer and neutrophils has recently
begun to emerge. This review will focus on recently published articles regarding …

Systemic treatment of renal cell carcinoma has changed dramatically since 2007, with the
development and approval of six new agents, which target complex molecular pathways …

Summary Background The International Metastatic Renal-Cell Carcinoma Database
Consortium model offers prognostic information for patients with metastatic renal-cell …

Background In previous clinical trials of patients with metastatic renal-cell carcinoma,
patients treated with axitinib as second-line therapy had longer median progression-free …

Background Clear-cell renal-cell carcinomas display divergent clinical behaviours.
However, the molecular genetic events driving these behaviours are unknown. We …

Purpose: If immune cells are involved in tumor surveillance and have a prognostic impact in
most primary tumors, little is known about their significance in metastases. Because patients' …

Purpose: The purpose of this guideline is to provide a clinical framework for follow-up of
clinically localized renal neoplasms undergoing active surveillance, or following definitive …

Background: The neutrophil–lymphocyte ratio (NLR) has been proposed as an indicator of
systemic inflammatory response. Several studies suggest a negative impact of increased …

BACKGROUND This study aimed to apply the International mRCC Database Consortium
(IMDC) prognostic model in metastatic non–clear cell renal cell carcinoma (nccRCC). In …

BACKGROUND Studies have shown that skeletal muscle and adipose tissue are linked to
overall survival (OS) and progression‐free survival (PFS). Because targeted therapies have …