Breast cancer is a heterogeneous disease affecting thousands of people every year.
Multiple factors are responsible in causing breast cancer while a number of treatment …

During the 1980s the structure–function relationship of nonsteroidal estrogens and
antiestrogens using an a prolactin gene target in primary cultures of rat pituitary cells created …

The application of synthetic organic chemistry to establish the simplest basic structure of
estrogenic compounds was a major triumph for medicinal chemistry in the 1930s. Two …

By the early 1970s, a number of metabolites of tamoxifen had been identified in animals and
following administration to a few patients. The hydroxylated metabolite of tamoxifen, 4 …

The clinical acceptance and validation of the therapeutic strategy of long-term adjuvant
tamoxifen treatment mandated an examination of acquired drug resistance under laboratory …

On January 20th 1961 John F. Kennedy was sworn in as the 35th President of the USA. In
his inaugural address he committed the US to sending a man to the moon, and returning him …