Chronic obstructive pulmonary disease (COPD) is a global health problem, and since 2001,
the Global Initiative for Chronic Obstructive Lung Disease (GOLD) has published its strategy …

Chronic bronchitis (CB) is a common but variable phenomenon in chronic obstructive
pulmonary disease (COPD). It has numerous clinical consequences, including an …

Rationale: Ambient air pollution has been suggested as a risk factor for chronic obstructive
pulmonary disease (COPD). However, there is a lack of longitudinal studies to support this …

Background Both long‐acting beta 2‐agonists and inhaled corticosteroids have been
recommended in guidelines for the treatment of chronic obstructive pulmonary disease …

There is increasing evidence that chronic obstructive pulmonary disease (COPD) is not
simply a disease of old age that is largely restricted to heavy smokers, but may be …

Chronic obstructive pulmonary disease (COPD) has traditionally been considered an
inexorably progressive disease, associated with a constant increase of symptoms that occur …

Augmentation therapy with the approved dose of 60 mg/kg weekly intravenous (IV) alpha-1
proteinase inhibitor (alpha1-PI), achieves a trough serum level of 11 μM in individuals with …

Introduction Chronic exposure to high levels of ozone induces emphysema and chronic
inflammation in mice. We determined the recovery from ozone-induced injury and whether …

The wide distribution of individual rates of decline in FEV 1 includes especially rapid and
slow declines. Future research is needed to identify biomarkers that both are predictive of a …

Chronic obstructive pulmonary disease (COPD) is a major public health problem because of
its high prevalence, rising incidence and associated socio-economic cost. The inhalation of …